Asb16 ankyrin repeat and SOCS box-containing 16 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Asb16provided by RGD
Official Full Name: ankyrin repeat and SOCS box-containing 16provided by RGD
Primary source: RGD:1563878
See related: Ensembl:ENSRNOG00000036794 AllianceGenome:RGD:1563878
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1563878
Summary: Predicted to be involved in intracellular signal transduction and protein ubiquitination. Orthologous to human ASB16 (ankyrin repeat and SOCS box containing 16). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward (RPKM 200.9) See more
Orthologs: human mouse all
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Genomic context

Location:: 10q32.1

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (87726128..87733228)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (87225976..87233078)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (90217979..90224984)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ankyrin repeat and SOCS box protein 16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001109048.1 → NP_001102518.1 ankyrin repeat and SOCS box protein 16

See identical proteins and their annotated locations for NP_001102518.1

Status: PROVISIONAL

Source sequence(s)

CH473948

UniProtKB/TrEMBL

A6HJH6, D4A8E5

Related

ENSRNOP00000028388.4, ENSRNOT00000028388.8

Conserved Domains (4) summary

cd00204
Location:170 → 304

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

cd03716
Location:406 → 446

SOCS_ASB_like; SOCS (suppressors of cytokine signaling) box of ASB (ankyrin repeat and SOCS box) and SSB (SPRY domain-containing SOCS box proteins) protein families. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence of a variable ...

pfam12796
Location:147 → 239

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:212 → 240

ANK; ANK repeat [structural motif]