Trat1 T cell receptor associated transmembrane adaptor 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Trat1provided by RGD
Official Full Name: T cell receptor associated transmembrane adaptor 1provided by RGD
Primary source: RGD:1563011
See related: Ensembl:ENSRNOG00000029564 AllianceGenome:RGD:1563011
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in negative regulation of receptor recycling and positive regulation of T cell receptor signaling pathway. Predicted to act upstream of or within negative regulation of transport and positive regulation of calcium-mediated signaling. Predicted to be located in centriolar satellite; mitotic spindle; and plasma membrane. Predicted to be part of T cell receptor complex. Orthologous to human TRAT1 (T cell receptor associated transmembrane adaptor 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Thymus (RPKM 345.6) and Spleen (RPKM 49.0) See more
Orthologs: human mouse all
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Genomic context

Location:: 11q21

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	11	NC_086029.1 (65498742..65540823)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	11	NC_051346.1 (52035750..52077805)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	11	NC_005110.4 (54619169..54661284)

Chromosome 11 - NC_086029.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in negative regulation of receptor recycling	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within negative regulation of receptor recycling	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within negative regulation of transport	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of T cell receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within positive regulation of T cell receptor signaling pathway	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of calcium-mediated signaling	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of T cell receptor complex	IBA Inferred from Biological aspect of Ancestor more info
part_of T cell receptor complex	ISO Inferred from Sequence Orthology more info
located_in centriolar satellite	IEA Inferred from Electronic Annotation more info
located_in centriolar satellite	ISO Inferred from Sequence Orthology more info
located_in mitotic spindle	IEA Inferred from Electronic Annotation more info
located_in mitotic spindle	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: T cell receptor associated transmembrane adaptor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.