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Wdr53 WD repeat domain 53 [ Rattus norvegicus (Norway rat) ]

Gene ID: 498097, updated on 13-Apr-2024

Summary

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Official Symbol
Wdr53provided by RGD
Official Full Name
WD repeat domain 53provided by RGD
Primary source
RGD:1559546
See related
Ensembl:ENSRNOG00000001754 AllianceGenome:RGD:1559546
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1559546
Summary
Orthologous to human WDR53 (WD repeat domain 53). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 51.5), Thymus (RPKM 27.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Wdr53 in Genome Data Viewer
Location:
11q22
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (82047674..82056217, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (68542647..68551148, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (71787454..71796258, complement)

Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 168 Neighboring gene single-pass membrane protein with coiled-coil domains 1 Neighboring gene small nucleolar RNA SNORA79 Neighboring gene F-box protein 45 Neighboring gene uncharacterized LOC134481089 Neighboring gene uncharacterized LOC120095670

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
WD repeat-containing protein 53

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109055.2 → NP_001102525.1  WD repeat-containing protein 53

    See identical proteins and their annotated locations for NP_001102525.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000011
    UniProtKB/TrEMBL
    A0A8I5ZLS1, A6IRS7, D4ADI9
    Related
    ENSRNOP00000002392.3, ENSRNOT00000002392.5
    Conserved Domains (2) summary
    sd00039
    Location:13 → 49
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:8 → 269
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. NM_001399295.1 → NP_001386224.1  WD repeat-containing protein 53

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000011
    UniProtKB/TrEMBL
    A6IRS7, D4ADI9
    Conserved Domains (2) summary
    sd00039
    Location:13 → 49
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:8 → 269
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. NM_001399296.1 → NP_001386225.1  WD repeat-containing protein 53

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000011
    UniProtKB/TrEMBL
    A6IRS7, D4ADI9
    Conserved Domains (2) summary
    sd00039
    Location:13 → 49
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:8 → 269
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086029.1 Reference GRCr8

    Range
    82047674..82056217 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063270707.1 → XP_063126777.1  WD repeat-containing protein 53 isoform X1

    UniProtKB/TrEMBL
    A6IRS7, D4ADI9

  2. XM_017598046.3 → XP_017453535.1  WD repeat-containing protein 53 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZLS1, A6IRS7, D4ADI9
    Conserved Domains (2) summary
    sd00039
    Location:13 → 49
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:8 → 269
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_063270708.1 → XP_063126778.1  WD repeat-containing protein 53 isoform X3

  4. XM_039088581.2 → XP_038944509.1  WD repeat-containing protein 53 isoform X3

    Conserved Domains (2) summary
    sd00039
    Location:40 → 78
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:40 → 124
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  5. XM_039088580.2 → XP_038944508.1  WD repeat-containing protein 53 isoform X2

    Conserved Domains (2) summary
    COG2319
    Location:30 → 183
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:36 → 72
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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