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Zfp518b zinc finger protein 518B [ Rattus norvegicus (Norway rat) ]

Gene ID: 498390, updated on 11-Apr-2024

Summary

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Official Symbol
Zfp518bprovided by RGD
Official Full Name
zinc finger protein 518Bprovided by RGD
Primary source
RGD:1564150
See related
Ensembl:ENSRNOG00000028534 AllianceGenome:RGD:1564150
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1564150
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF518B (zinc finger protein 518B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See Zfp518b in Genome Data Viewer
Location:
14q21
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (76333582..76352804)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (72121085..72140479)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (76853171..76872476)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene cytokine-dependent hematopoietic cell linker Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC120096632 Neighboring gene U6 spliceosomal RNA Neighboring gene non-POU domain containing, octamer-binding, pseudogene 12 Neighboring gene ribonucleotide reductase M1, pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 518B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    76333582..76352804
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017599488.3 → XP_017454977.1  zinc finger protein 518B isoform X1

    UniProtKB/TrEMBL
    A6IJS9, D4ABC6
    Related
    ENSRNOP00000097304.1
    Conserved Domains (2) summary
    sd00017
    Location:140 → 160
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:179 → 200
    zf-H2C2_2; Zinc-finger double domain

  2. XM_008770231.4 → XP_008768453.1  zinc finger protein 518B isoform X1

    See identical proteins and their annotated locations for XP_008768453.1

    UniProtKB/TrEMBL
    A6IJS9, D4ABC6
    Related
    ENSRNOP00000084723.1
    Conserved Domains (2) summary
    sd00017
    Location:140 → 160
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:179 → 200
    zf-H2C2_2; Zinc-finger double domain

  3. XM_039092820.1 → XP_038948748.1  zinc finger protein 518B isoform X2

    Conserved Domains (2) summary
    sd00017
    Location:140 → 160
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13909
    Location:167 → 189
    zf-H2C2_5; C2H2-type zinc-finger domain

  4. XM_039092821.2 → XP_038948749.1  zinc finger protein 518B isoform X3

    Conserved Domains (2) summary
    sd00017
    Location:140 → 160
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13909
    Location:167 → 189
    zf-H2C2_5; C2H2-type zinc-finger domain

RNA

  1. XR_005493342.2 RNA Sequence

  2. XR_005493343.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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