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Fam107b family with sequence similarity 107, member B [ Rattus norvegicus (Norway rat) ]

Gene ID: 498796, updated on 24-Apr-2024

Summary

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Official Symbol
Fam107bprovided by RGD
Official Full Name
family with sequence similarity 107, member Bprovided by RGD
Primary source
RGD:1561482
See related
Ensembl:ENSRNOG00000014886 AllianceGenome:RGD:1561482
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to act upstream of or within sensory perception of sound. Orthologous to human FAM107B (family with sequence similarity 107 member B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 476.2), Testes (RPKM 259.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
17q12.3
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (79387795..79594165, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (74478608..74685027, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (78489667..78689933, complement)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene FERM domain containing 4A Neighboring gene uncharacterized LOC134482744 Neighboring gene uncharacterized LOC102554651 Neighboring gene uncharacterized LOC108348592 Neighboring gene uncharacterized LOC120097880 Neighboring gene uncharacterized LOC120097879 Neighboring gene uncharacterized LOC134482747 Neighboring gene Myb/SANT DNA binding domain containing 7 Neighboring gene heat shock protein family A (Hsp70) member 14 Neighboring gene cerebral dopamine neurotrophic factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. White JK, et al. Cell, 2013 Jul 18. PMID 23870131, Free PMC Article
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within sensory perception of sound ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein FAM107B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025034.2 → NP_001020205.1  protein FAM107B isoform 1

    See identical proteins and their annotated locations for NP_001020205.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000017
    UniProtKB/Swiss-Prot
    Q5U4F3
    UniProtKB/TrEMBL
    A0A8I5ZR87, A6JM08
    Conserved Domains (1) summary
    pfam06625
    Location:9 → 120
    DUF1151; Protein of unknown function (DUF1151)

  2. NM_001401503.1 → NP_001388432.1  protein FAM107B isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000017
    UniProtKB/Swiss-Prot
    Q5U4F3
    UniProtKB/TrEMBL
    A6JM08
    Related
    ENSRNOP00000085064.1, ENSRNOT00000105947.1

  3. NM_001429379.1 → NP_001416308.1  protein FAM107B isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000017

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    79387795..79594165 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017600646.3 → XP_017456135.1  protein FAM107B isoform X1

    UniProtKB/TrEMBL
    A0A8I5Y0Q3
    Related
    ENSRNOP00000077094.1

  2. XM_063276704.1 → XP_063132774.1  protein FAM107B isoform X6

    UniProtKB/Swiss-Prot
    Q5U4F3
    UniProtKB/TrEMBL
    A6JM08

  3. XM_008771884.4 → XP_008770106.1  protein FAM107B isoform X6

    See identical proteins and their annotated locations for XP_008770106.1

    UniProtKB/Swiss-Prot
    Q5U4F3
    UniProtKB/TrEMBL
    A0A8I5ZR87, A6JM08
    Conserved Domains (1) summary
    pfam06625
    Location:9 → 120
    DUF1151; Protein of unknown function (DUF1151)

  4. XM_063276703.1 → XP_063132773.1  protein FAM107B isoform X6

    UniProtKB/Swiss-Prot
    Q5U4F3
    UniProtKB/TrEMBL
    A6JM08

  5. XM_008771880.4 → XP_008770102.1  protein FAM107B isoform X4

    UniProtKB/TrEMBL
    A0A8I6A9X6, A0A8L2QA46
    Related
    ENSRNOP00000020220.4
    Conserved Domains (1) summary
    pfam06625
    Location:38 → 150
    DUF1151; Protein of unknown function (DUF1151)

  6. XM_039096026.2 → XP_038951954.1  protein FAM107B isoform X3

    UniProtKB/TrEMBL
    A0A8I6A9X6
    Conserved Domains (1) summary
    pfam06625
    Location:64 → 175
    DUF1151; Protein of unknown function (DUF1151)

  7. XM_039096027.2 → XP_038951955.1  protein FAM107B isoform X6

    UniProtKB/Swiss-Prot
    Q5U4F3
    UniProtKB/TrEMBL
    A0A8I5ZR87, A6JM08
    Conserved Domains (1) summary
    pfam06625
    Location:9 → 120
    DUF1151; Protein of unknown function (DUF1151)

  8. XM_008771881.4 → XP_008770103.1  protein FAM107B isoform X5

    UniProtKB/TrEMBL
    A0A0G2JV46, A0A8I5ZR87
    Related
    ENSRNOP00000069346.1
    Conserved Domains (1) summary
    pfam06625
    Location:36 → 148
    DUF1151; Protein of unknown function (DUF1151)

  9. XM_017600647.3 → XP_017456136.1  protein FAM107B isoform X2

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5U4F3.1 GenPept UniProtKB/Swiss-Prot:Q5U4F3

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