Fam170a family with sequence similarity 170, member A [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Fam170aprovided by RGD
Official Full Name: family with sequence similarity 170, member Aprovided by RGD
Primary source: RGD:1565393
See related: Ensembl:ENSRNOG00000015834 AllianceGenome:RGD:1565393
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1565393
Summary: Predicted to be involved in fertilization; positive regulation of transcription, DNA-templated; and transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human FAM170A (family with sequence similarity 170 member A). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward (RPKM 134.2) See more
Orthologs: human mouse all
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Genomic context

Location:: 18q11

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	18	NC_086036.1 (45707817..45712548)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	18	NC_051353.1 (43521304..43526035)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	18	NC_005117.4 (45023910..45028670)

Chromosome 18 - NC_086036.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in fertilization	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: protein FAM170A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001126293.2 → NP_001119765.2 protein FAM170A

Status: VALIDATED

Source sequence(s)

JAXUCZ010000018

UniProtKB/TrEMBL

B1H287

Conserved Domains (1) summary

pfam17734
Location:153 → 270

Spt46; Spermatogenesis-associated protein 46