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Strip2 striatin interacting protein 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 500066, updated on 6-Jun-2024

Summary

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Official Symbol
Strip2provided by RGD
Official Full Name
striatin interacting protein 2provided by RGD
Primary source
RGD:1588437
See related
Ensembl:ENSRNOG00000057729 AllianceGenome:RGD:1588437
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in cell migration; cytoskeleton organization; and regulation of cell shape. Predicted to be located in cytosol. Orthologous to human STRIP2 (striatin interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 133.0), Heart (RPKM 69.1) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Strip2 in Genome Data Viewer
Location:
4q22
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (59503478..59545745)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (58536034..58578279)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (57204850..57248912)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120102483 Neighboring gene adenosylhomocysteinase-like 2 Neighboring gene large ribosomal subunit protein eL19-like Neighboring gene phosphoglycerate kinase 1, pseudogene 1 Neighboring gene small lysine-rich protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration. Bai SW, et al. BMC Biol, 2011 Aug 11. PMID 21834987, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in cell migration ISO
Inferred from Sequence Orthology
more info
  
involved_in cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of cell shape ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of FAR/SIN/STRIPAK complex ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
striatin-interacting protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427848.1 → NP_001414777.1  striatin-interacting protein 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000004
    UniProtKB/TrEMBL
    A0A8I5ZP29, A0A8I6G7M4

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    59503478..59545745
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063286497.1 → XP_063142567.1  striatin-interacting protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZP29, A0A8I6G7M4

  2. XM_063286498.1 → XP_063142568.1  striatin-interacting protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZP29, A0A8I6G7M4

  3. XM_063286499.1 → XP_063142569.1  striatin-interacting protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8I5ZP29

  4. XM_063286500.1 → XP_063142570.1  striatin-interacting protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8I5ZP29
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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