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Zfp467 zinc finger protein 467 [ Rattus norvegicus (Norway rat) ]

Gene ID: 500110, updated on 5-Mar-2024

Summary

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Official Symbol
Zfp467provided by RGD
Official Full Name
zinc finger protein 467provided by RGD
Primary source
RGD:1561603
See related
Ensembl:ENSRNOG00000007707 AllianceGenome:RGD:1561603
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Znf467
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be active in nucleus. Orthologous to human ZNF467 (zinc finger protein 467). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 39.5), Lung (RPKM 30.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfp467 in Genome Data Viewer
Location:
4q24
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (78716473..78725829, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (77385752..77394709, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (78068822..78077962, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486766 Neighboring gene transfer RNA cysteine (anticodon GCA) 28 Neighboring gene KRAB-A domain containing 1 Neighboring gene SCO-spondin Neighboring gene uncharacterized LOC120102263 Neighboring gene zinc finger protein 862

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription activator activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
zinc finger protein 467

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024327.1 → NP_001019498.1  zinc finger protein 467

    See identical proteins and their annotated locations for NP_001019498.1

    Status: PROVISIONAL

    Source sequence(s)
    BC086534
    UniProtKB/Swiss-Prot
    Q5RJR4
    UniProtKB/TrEMBL
    A6K0E7
    Related
    ENSRNOP00000010377.4, ENSRNOT00000010377.7
    Conserved Domains (4) summary
    COG5048
    Location:190 → 564
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:218 → 238
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:216 → 238
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:230 → 255
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    78716473..78725829 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017592790.3 → XP_017448279.1  zinc finger protein 467 isoform X2

    UniProtKB/TrEMBL
    A0A0G2K5V9

  2. XM_006236433.5 → XP_006236495.1  zinc finger protein 467 isoform X1

    See identical proteins and their annotated locations for XP_006236495.1

    UniProtKB/Swiss-Prot
    Q5RJR4
    UniProtKB/TrEMBL
    A6K0E7
    Conserved Domains (4) summary
    COG5048
    Location:190 → 564
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:218 → 238
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:216 → 238
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:230 → 255
    zf-H2C2_2; Zinc-finger double domain

  3. XM_006236432.5 → XP_006236494.1  zinc finger protein 467 isoform X1

    See identical proteins and their annotated locations for XP_006236494.1

    UniProtKB/Swiss-Prot
    Q5RJR4
    UniProtKB/TrEMBL
    A6K0E7
    Conserved Domains (4) summary
    COG5048
    Location:190 → 564
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:218 → 238
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:216 → 238
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:230 → 255
    zf-H2C2_2; Zinc-finger double domain

  4. XM_006236434.5 → XP_006236496.1  zinc finger protein 467 isoform X1

    See identical proteins and their annotated locations for XP_006236496.1

    UniProtKB/Swiss-Prot
    Q5RJR4
    UniProtKB/TrEMBL
    A6K0E7
    Conserved Domains (4) summary
    COG5048
    Location:190 → 564
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:218 → 238
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:216 → 238
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:230 → 255
    zf-H2C2_2; Zinc-finger double domain

  5. XM_006236431.5 → XP_006236493.1  zinc finger protein 467 isoform X1

    See identical proteins and their annotated locations for XP_006236493.1

    UniProtKB/Swiss-Prot
    Q5RJR4
    UniProtKB/TrEMBL
    A6K0E7
    Conserved Domains (4) summary
    COG5048
    Location:190 → 564
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:218 → 238
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:216 → 238
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:230 → 255
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5RJR4.1 GenPept UniProtKB/Swiss-Prot:Q5RJR4

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