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Heatr4 HEAT repeat containing 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 500692, updated on 5-Mar-2024

Summary

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Official Symbol
Heatr4provided by RGD
Official Full Name
HEAT repeat containing 4provided by RGD
Primary source
RGD:1566220
See related
Ensembl:ENSRNOG00000038183 AllianceGenome:RGD:1566220
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1566220
Summary
Predicted to enable oxidoreductase activity. Orthologous to human HEATR4 (HEAT repeat containing 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 137.9) and Thymus (RPKM 5.6) See more
Orthologs
human mouse all
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Genomic context

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See Heatr4 in Genome Data Viewer
Location:
6q31
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (109305459..109338331, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (103574360..103611578, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (107423214..107460450, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene presenilin 1 Neighboring gene papilin, proteoglycan-like sulfated glycoprotein Neighboring gene NUMB, endocytic adaptor protein Neighboring gene uncharacterized LOC134479228 Neighboring gene uncharacterized LOC134479229 Neighboring gene ribosomal oxygenase 1 Neighboring gene acyl-CoA thioesterase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
HEAT repeat-containing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    109305459..109338331 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006240361.5 → XP_006240423.1  HEAT repeat-containing protein 4 isoform X2

    See identical proteins and their annotated locations for XP_006240423.1

    UniProtKB/TrEMBL
    D3ZSB9
    Conserved Domains (2) summary
    pfam13646
    Location:680 → 802
    HEAT_2; HEAT repeats
    sd00044
    Location:681 → 708
    HEAT; HEAT repeat [structural motif]

  2. XM_063262680.1 → XP_063118750.1  HEAT repeat-containing protein 4 isoform X1

  3. XM_006240362.4 → XP_006240424.1  HEAT repeat-containing protein 4 isoform X2

    See identical proteins and their annotated locations for XP_006240424.1

    UniProtKB/TrEMBL
    D3ZSB9
    Conserved Domains (2) summary
    pfam13646
    Location:680 → 802
    HEAT_2; HEAT repeats
    sd00044
    Location:681 → 708
    HEAT; HEAT repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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