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Bbof1 basal body orientation factor 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 500693, updated on 11-Apr-2024

Summary

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Official Symbol
Bbof1provided by RGD
Official Full Name
basal body orientation factor 1provided by RGD
Primary source
RGD:1560978
See related
Ensembl:ENSRNOG00000011376 AllianceGenome:RGD:1560978
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ccdc176; RGD1560978
Summary
Predicted to be located in ciliary basal body and cytoplasm. Orthologous to human BBOF1 (basal body orientation factor 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 1049.3), Liver (RPKM 591.5) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Bbof1 in Genome Data Viewer
Location:
6q31
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (109786363..109812153)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (104055246..104081036)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (108123855..108149613)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 410 Neighboring gene FAM161 centrosomal protein B Neighboring gene coenzyme Q6 monooxygenase Neighboring gene ectonucleoside triphosphate diphosphohydrolase 5 Neighboring gene ring finger protein 113A2 Neighboring gene aldehyde dehydrogenase 6 family, member A1 Neighboring gene lin-52 DREAM MuvB core complex component Neighboring gene visual system homeobox 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in flagellated sperm motility ISO
Inferred from Sequence Orthology
more info
  
involved_in sperm axoneme assembly ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in axoneme ISO
Inferred from Sequence Orthology
more info
  
located_in sperm flagellum ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
basal body-orientation factor 1
Names
coiled-coil domain containing 176

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001395618.1 → NP_001382547.1  basal body-orientation factor 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A0A8I6G3Y3
    Related
    ENSRNOP00000079957.1, ENSRNOT00000098589.1
    Conserved Domains (1) summary
    pfam14988
    Location:75 → 268
    DUF4515; Domain of unknown function (DUF4515)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    109786363..109812153
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063262320.1 → XP_063118390.1  basal body-orientation factor 1 isoform X2

  2. XM_008764830.4 → XP_008763052.3  basal body-orientation factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A0G2K4P4

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001134631.1: Suppressed sequence

    Description
    NM_001134631.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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