Slc37a2 solute carrier family 37 member 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc37a2provided by RGD
Official Full Name: solute carrier family 37 member 2provided by RGD
Primary source: RGD:1564160
See related: Ensembl:ENSRNOG00000039390 AllianceGenome:RGD:1564160
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1564160
Summary: Predicted to enable glucose 6-phosphate:inorganic phosphate antiporter activity. Predicted to be involved in glucose-6-phosphate transport and phosphate ion transmembrane transport. Predicted to be integral component of endoplasmic reticulum membrane. Orthologous to human SLC37A2 (solute carrier family 37 member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Testes (RPKM 35.3), Spleen (RPKM 29.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q22

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (45134596..45160551, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (36945787..36971748, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (39708678..39735042, complement)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables glucose 6-phosphate:phosphate antiporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables glucose 6-phosphate:phosphate antiporter activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in glucose-6-phosphate transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in glucose-6-phosphate transport	ISO Inferred from Sequence Orthology more info
involved_in phosphate ion transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in phosphate ion transmembrane transport	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: glucose-6-phosphate exchanger SLC37A2

Names: solute carrier family 37 (glucose-6-phosphate transporter), member 2; solute carrier family 37 (glycerol-3-phosphate transporter), member 2; sugar phosphate exchanger 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191994.2 → NP_001178923.1 glucose-6-phosphate exchanger SLC37A2 isoform 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000008

UniProtKB/TrEMBL

A0A096MJU4, A0A8I6AHQ7

Related

ENSRNOP00000068265.2, ENSRNOT00000076872.3

Conserved Domains (2) summary

cd06174
Location:86 → 481

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

TIGR00881
Location:77 → 463

2A0104; phosphoglycerate transporter family protein
NM_001412516.1 → NP_001399445.1 glucose-6-phosphate exchanger SLC37A2 isoform 2

Status: VALIDATED

Source sequence(s)

JAXUCZ010000008

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086026.1 Reference GRCr8

Range

45134596..45160551 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039081929.2 → XP_038937857.1 glucose-6-phosphate exchanger SLC37A2 isoform X1

UniProtKB/TrEMBL

A6KRM0

Related

ENSRNOP00000073837.2

Conserved Domains (1) summary

cd17344
Location:14 → 476

MFS_SLC37A1_2; Solute carrier family 37 members 1 and 2 of the Major Facilitator Superfamily of transporters