Slc25a36 solute carrier family 25 member 36 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc25a36provided by RGD
Official Full Name: solute carrier family 25 member 36provided by RGD
Primary source: RGD:1591928
See related: Ensembl:ENSRNOG00000013802 AllianceGenome:RGD:1591928
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable pyrimidine nucleotide transmembrane transporter activity. Predicted to be involved in mitochondrial genome maintenance; pyrimidine nucleotide import into mitochondrion; and regulation of mitochondrial membrane potential. Predicted to be located in mitochondrion. Orthologous to human SLC25A36 (solute carrier family 25 member 36). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Kidney (RPKM 545.6), Lung (RPKM 416.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q31

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (106539355..106573240, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (97659848..97693735, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (104962569..104995935, complement)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

BF399367 (e-PCR)
- UniSTS:247653

RH135209 (e-PCR)
- UniSTS:218486

BF399456 (e-PCR)
- UniSTS:247687

RH142614 (e-PCR)
- UniSTS:231861

NoName (e-PCR)
- UniSTS:547052

Slc25a36 (e-PCR), detects polymorphism
- UniSTS:547052

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables pyrimidine nucleotide transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables pyrimidine nucleotide transmembrane transporter activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in mitochondrial genome maintenance	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial genome maintenance	ISO Inferred from Sequence Orthology more info
involved_in mitochondrion organization	ISO Inferred from Sequence Orthology more info
involved_in pyrimidine nucleotide import into mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
involved_in pyrimidine nucleotide transport	ISO Inferred from Sequence Orthology more info
involved_in regulation of mitochondrial membrane potential	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: solute carrier family 25 member 36

Names: solute carrier family 25 (pyrimidine nucleotide carrier ), member 36

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001427729.1 → NP_001414658.1 solute carrier family 25 member 36

Status: VALIDATED

Source sequence(s)

JAXUCZ010000008

UniProtKB/TrEMBL

A0A0G2JV03, D4ACN9

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086026.1 Reference GRCr8

Range

106539355..106573240 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_008766577.4 → XP_008764799.1 solute carrier family 25 member 36 isoform X1

See identical proteins and their annotated locations for XP_008764799.1

UniProtKB/TrEMBL

A0A0G2JV03

Conserved Domains (1) summary

pfam00153
Location:88 → 180

Mito_carr; Mitochondrial carrier protein
XM_063265997.1 → XP_063122067.1 solute carrier family 25 member 36 isoform X2
XM_063265996.1 → XP_063122066.1 solute carrier family 25 member 36 isoform X2
XM_039082574.2 → XP_038938502.1 solute carrier family 25 member 36 isoform X2

Conserved Domains (1) summary

pfam00153
Location:30 → 105

Mito_carr; Mitochondrial carrier protein
XM_039082571.2 → XP_038938499.1 solute carrier family 25 member 36 isoform X2

Conserved Domains (1) summary

pfam00153
Location:30 → 105

Mito_carr; Mitochondrial carrier protein