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Yju2 YJU2 splicing factor [ Rattus norvegicus (Norway rat) ]

Gene ID: 501285, updated on 5-Mar-2024

Summary

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Official Symbol
Yju2provided by RGD
Official Full Name
YJU2 splicing factorprovided by RGD
Primary source
RGD:1589601
See related
Ensembl:ENSRNOG00000047456 AllianceGenome:RGD:1589601
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ccdc94
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in RNA splicing. Predicted to be part of U2-type catalytic step 1 spliceosome. Orthologous to human YJU2 (YJU2 splicing factor homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 131.0), Spleen (RPKM 100.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Yju2 in Genome Data Viewer
Location:
9q11
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (876790..886687)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (789603..799505)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (11098914..11108806, complement)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 119b like Neighboring gene small nucleolar RNA SNORA48 Neighboring gene ribosomal protein S21, pseudogene 2 Neighboring gene Epstein-Barr virus induced 3 Neighboring gene uncharacterized LOC134480467 Neighboring gene src homology 2 domain-containing transforming protein D Neighboring gene fibronectin type III and SPRY domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Structure of a human catalytic step I spliceosome. Zhan X, et al. Science, 2018 Feb 2. PMID 29301961
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC156684

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in RNA splicing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in generation of catalytic spliceosome for first transesterification step IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of U2-type catalytic step 1 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U2-type catalytic step 1 spliceosome ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
splicing factor YJU2
Names
YJU2 splicing factor homolog
coiled-coil domain containing 94
coiled-coil domain-containing protein 94

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109673.1 → NP_001103143.1  splicing factor YJU2

    See identical proteins and their annotated locations for NP_001103143.1

    Status: PROVISIONAL

    Source sequence(s)
    BC169032
    UniProtKB/TrEMBL
    A2VD11, A6KR23
    Related
    ENSRNOP00000067468.2, ENSRNOT00000072357.2
    Conserved Domains (2) summary
    COG5134
    Location:7 → 178
    COG5134; Uncharacterized conserved protein [Function unknown]
    pfam04502
    Location:8 → 262
    DUF572; Family of unknown function (DUF572)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    876790..886687
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006244336.5 → XP_006244398.1  splicing factor YJU2 isoform X1

    UniProtKB/TrEMBL
    A6KR23
    Conserved Domains (2) summary
    COG5134
    Location:7 → 178
    COG5134; Uncharacterized conserved protein [Function unknown]
    pfam04502
    Location:8 → 177
    DUF572; Family of unknown function (DUF572)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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