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hist1h2ail2 histone cluster 1, H2ai-like2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 502129, updated on 13-Apr-2024

Summary

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Official Symbol
hist1h2ail2provided by RGD
Official Full Name
histone cluster 1, H2ai-like2provided by RGD
Primary source
RGD:1562827
See related
AllianceGenome:RGD:1562827
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Hist1h2ai; RGD1562827
Summary
Predicted to enable protein heterodimerization activity. Predicted to be located in nucleus. Predicted to be part of nucleosome. Orthologous to human H2AC4 (H2A clustered histone 4). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
17p11
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (47448902..47449362)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (42753160..42753620)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (44794087..44794563)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene H1.5 linker histone, cluster member Neighboring gene H2B clustered histone like 1 Neighboring gene oligosaccharyltransferase complex subunit 4, non-catalytic, pseudogene 1 Neighboring gene histone H4C like 3 Neighboring gene histone cluster 1 H2B family member D

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Increasing the complexity of chromatin: functionally distinct roles for replication-dependent histone H2A isoforms in cell proliferation and carcinogenesis. Singh R, et al. Nucleic Acids Res, 2013 Nov. PMID 23956221, Free PMC Article
  2. Precise characterization of human histones in the H2A gene family by top down mass spectrometry. Boyne MT 2nd, et al. J Proteome Res, 2006 Feb. PMID 16457589
  3. Characterization of histone H2A and H2B variants and their post-translational modifications by mass spectrometry. Bonenfant D, et al. Mol Cell Proteomics, 2006 Mar. PMID 16319397
  4. Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Gonzalez-Begne M, et al. J Proteome Res, 2009 Mar. PMID 19199708, Free PMC Article
  5. Proteomic characterization of the human sperm nucleus. de Mateo S, et al. Proteomics, 2011 Jul. PMID 21630459

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
histone cluster 1, H2ai-like2
Names
histone H2A type 1
histone H2A type 1-B
histone cluster 1, H2ai

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001408761.1 → NP_001395690.1  histone cluster 1, H2ai-like2

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000017
    UniProtKB/TrEMBL
    A6KLN9, G3V9C0

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    47448902..47449362
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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