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Rbpms2 RNA binding protein, mRNA processing factor 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 503214, updated on 20-Apr-2024

Summary

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Official Symbol
Rbpms2provided by RGD
Official Full Name
RNA binding protein, mRNA processing factor 2provided by RGD
Primary source
RGD:1561222
See related
Ensembl:ENSRNOG00000015896 AllianceGenome:RGD:1561222
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1561222
Summary
Predicted to enable mRNA binding activity and protein homodimerization activity. Predicted to be involved in negative regulation of smooth muscle cell differentiation. Predicted to be active in cytoplasm. Orthologous to human RBPMS2 (RNA binding protein, mRNA processing factor 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 94.3), Heart (RPKM 63.0) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Rbpms2 in Genome Data Viewer
Location:
8q24
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (75048159..75079393)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (66153169..66184278)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (71165375..71200299)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene pleckstrin homology domain containing O2 Neighboring gene PIF1 5'-to-3' DNA helicase Neighboring gene uncharacterized LOC103693122 Neighboring gene ornithine decarboxylase antizyme 2 Neighboring gene zinc finger protein 609

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Expression of hermes gene is restricted to the ganglion cells in the retina. Piri N, et al. Neurosci Lett, 2006 Sep 11. PMID 16870336
  2. Homodimerization of RBPMS2 through a new RRM-interaction motif is necessary to control smooth muscle plasticity. Sagnol S, et al. Nucleic Acids Res, 2014 Sep. PMID 25064856, Free PMC Article
  3. Mapping the in vitro interactome of cardiac sodium (Na(+) )-calcium (Ca(2+) ) exchanger 1 (NCX1). Lubelwana Hafver T, et al. Proteomics, 2017 Sep. PMID 28755400
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC189424

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mRNA binding ISO
Inferred from Sequence Orthology
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in negative regulation of smooth muscle cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of smooth muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of alternative mRNA splicing, via spliceosome IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasmic stress granule ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
RNA binding protein, mRNA processing factor 2; RNA-binding protein with multiple splicing 2
Names
RNA binding protein with multiple splicing 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001173426.1 → NP_001166897.1  RNA binding protein, mRNA processing factor 2

    See identical proteins and their annotated locations for NP_001166897.1

    Status: PROVISIONAL

    Source sequence(s)
    BC169038
    UniProtKB/Swiss-Prot
    B5DFF2, F1M9N3
    Related
    ENSRNOP00000021337.6, ENSRNOT00000021337.8
    Conserved Domains (1) summary
    cd12683
    Location:30 → 105
    RRM_RBPMS2; RNA recognition motif in vertebrate RNA-binding protein with multiple splicing 2 (RBP-MS2)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    75048159..75079393
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006243274.5 → XP_006243336.1  RNA-binding protein with multiple splicing 2 isoform X1

    See identical proteins and their annotated locations for XP_006243336.1

    UniProtKB/Swiss-Prot
    B5DFF2, F1M9N3
    Conserved Domains (1) summary
    cd12683
    Location:30 → 105
    RRM_RBPMS2; RNA recognition motif in vertebrate RNA-binding protein with multiple splicing 2 (RBP-MS2)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B5DFF2.1 GenPept UniProtKB/Swiss-Prot:B5DFF2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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