U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Dbx2 developing brain homeobox 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 541457, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Symbol
Dbx2provided by RGD
Full Name
developing brain homeobox 2provided by RGD
Primary source
RGD:1359605
See related
Ensembl:ENSRNOG00000006885 AllianceGenome:RGD:1359605
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human DBX2 (developing brain homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 24.4) See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Dbx2 in Genome Data Viewer
Location:
7q35
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (128651603..128681886, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (126772389..126802625, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (136966879..136997104, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene neural EGFL like 2 Neighboring gene U4 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC102547300 Neighboring gene anoctamin 6 Neighboring gene uncharacterized LOC134479558 Neighboring gene histone deacetylase 1-like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Expression study of cadherin7 and cadherin20 in the embryonic and adult rat central nervous system. Takahashi M, et al. BMC Dev Biol, 2008 Sep 19. PMID 18801203, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
homeobox protein DBX2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    128651603..128681886 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006242286.4 → XP_006242348.1  homeobox protein DBX2 isoform X2

    See identical proteins and their annotated locations for XP_006242348.1

    UniProtKB/TrEMBL
    A6KC08
    Conserved Domains (1) summary
    pfam00046
    Location:197 → 250
    Homeobox; Homeobox domain

  2. XM_001053826.6 → XP_001053826.1  homeobox protein DBX2 isoform X1

    See identical proteins and their annotated locations for XP_001053826.1

    UniProtKB/TrEMBL
    A6KC08, F1LRM4
    Related
    ENSRNOP00000009143.4
    Conserved Domains (1) summary
    pfam00046
    Location:229 → 282
    Homeobox; Homeobox domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous