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Pcnx1 pecanex 1 [ Mus musculus (house mouse) ]

Gene ID: 54604, updated on 5-Mar-2024

Summary

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Official Symbol
Pcnx1provided by MGI
Official Full Name
pecanex 1provided by MGI
Primary source
MGI:MGI:1891924
See related
Ensembl:ENSMUSG00000021140 AllianceGenome:MGI:1891924
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pcnx; Pcnxl1; 2900024E21Rik; 3526401J03Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in cerebral cortex marginal layer; lateral ventricle choroid plexus; medulla oblongata basal plate mantle layer; and metencephalon part of 4th ventricle choroid plexus. Orthologous to human PCNX1 (pecanex 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in lung adult (RPKM 13.9), ovary adult (RPKM 11.9) and 26 other tissues See more
Orthologs
human all
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Genomic context

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See Pcnx1 in Genome Data Viewer
Location:
12 D1; 12 37.98 cM
Exon count:
36
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (81906688..82047698)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (81859913..82000924)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase 9 Neighboring gene STARR-positive B cell enhancer ABC_E4034 Neighboring gene STARR-seq mESC enhancer starr_32680 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:82893600-82893709 Neighboring gene STARR-seq mESC enhancer starr_32681 Neighboring gene predicted gene, 30706 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:83072406-83072559 Neighboring gene STARR-seq mESC enhancer starr_32682 Neighboring gene predicted gene, 30799 Neighboring gene STARR-seq mESC enhancer starr_32683 Neighboring gene STARR-positive B cell enhancer ABC_E7158 Neighboring gene signal-induced proliferation-associated 1 like 1 Neighboring gene STARR-positive B cell enhancer ABC_E4035 Neighboring gene STARR-positive B cell enhancer ABC_E11517 Neighboring gene predicted gene, 30916

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity. Galazo MJ, et al. Neuron, 2016 Jul 6. PMID 27321927, Free PMC Article
  2. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579
  3. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Aug 31. PMID 14621295
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
pecanex-like protein 1
Names
pecanex homolog protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018814.3 → NP_061284.2  pecanex-like protein 1

    See identical proteins and their annotated locations for NP_061284.2

    Status: VALIDATED

    Source sequence(s)
    AC124484, AK129221, BP753289, CF182434, CF746564, CJ107156, CN535767
    Consensus CDS
    CCDS26025.1
    UniProtKB/Swiss-Prot
    Q6ZQ41, Q9CUU7, Q9QYC1
    Related
    ENSMUSP00000021567.6, ENSMUST00000021567.6
    Conserved Domains (4) summary
    COG1266
    Location:993 → 1229
    YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
    pfam05041
    Location:1785 → 2009
    Pecanex_C; Pecanex protein (C-terminus)
    pfam12730
    Location:1035 → 1282
    ABC2_membrane_4; ABC-2 family transporter protein
    cl11542
    Location:1402 → 1527
    EcsB; Bacterial ABC transporter protein EcsB

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    81906688..82047698
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516090.4 → XP_006516153.1  pecanex-like protein 1 isoform X2

    Conserved Domains (3) summary
    PHA03307
    Location:330 → 616
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1780 → 2006
    Pecanex_C; Pecanex protein (C-terminus)
    cl11542
    Location:1397 → 1522
    EcsB; Bacterial ABC transporter protein EcsB

  2. XM_006516089.4 → XP_006516152.1  pecanex-like protein 1 isoform X1

    Conserved Domains (3) summary
    PHA03307
    Location:330 → 616
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1784 → 2010
    Pecanex_C; Pecanex protein (C-terminus)
    cl11542
    Location:1401 → 1526
    EcsB; Bacterial ABC transporter protein EcsB

  3. XM_006516091.4 → XP_006516154.1  pecanex-like protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A1Y7VKR5
    Related
    ENSMUSP00000152104.2, ENSMUST00000221721.2
    Conserved Domains (3) summary
    PHA03307
    Location:330 → 616
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1779 → 2005
    Pecanex_C; Pecanex protein (C-terminus)
    cl11542
    Location:1396 → 1521
    EcsB; Bacterial ABC transporter protein EcsB

  4. XM_006516092.4 → XP_006516155.1  pecanex-like protein 1 isoform X4

    Conserved Domains (3) summary
    PHA03307
    Location:330 → 616
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1679 → 1905
    Pecanex_C; Pecanex protein (C-terminus)
    cl11542
    Location:1296 → 1421
    EcsB; Bacterial ABC transporter protein EcsB

  5. XM_006516093.4 → XP_006516156.1  pecanex-like protein 1 isoform X5

    Conserved Domains (3) summary
    PHA03307
    Location:330 → 616
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1674 → 1900
    Pecanex_C; Pecanex protein (C-terminus)
    cl11542
    Location:1291 → 1416
    EcsB; Bacterial ABC transporter protein EcsB

  6. XM_030246823.2 → XP_030102683.1  pecanex-like protein 1 isoform X6

    Conserved Domains (2) summary
    PHA03307
    Location:5 → 138
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam05041
    Location:1307 → 1533
    Pecanex_C; Pecanex protein (C-terminus)

  7. XM_006516095.4 → XP_006516158.1  pecanex-like protein 1 isoform X8

    See identical proteins and their annotated locations for XP_006516158.1

    UniProtKB/TrEMBL
    Q6PG01
    Conserved Domains (1) summary
    pfam05041
    Location:887 → 1113
    Pecanex_C; Pecanex protein (C-terminus)

  8. XM_036157537.1 → XP_036013430.1  pecanex-like protein 1 isoform X8

    UniProtKB/TrEMBL
    Q6PG01
    Conserved Domains (1) summary
    pfam05041
    Location:887 → 1113
    Pecanex_C; Pecanex protein (C-terminus)

  9. XM_017315138.3 → XP_017170627.1  pecanex-like protein 1 isoform X9

    UniProtKB/TrEMBL
    Q3TD89
    Conserved Domains (1) summary
    pfam05041
    Location:642 → 868
    Pecanex_C; Pecanex protein (C-terminus)

  10. XM_006516094.4 → XP_006516157.1  pecanex-like protein 1 isoform X7

    UniProtKB/TrEMBL
    Q6PG01
    Conserved Domains (1) summary
    pfam05041
    Location:892 → 1118
    Pecanex_C; Pecanex protein (C-terminus)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9QYC1.3 GenPept UniProtKB/Swiss-Prot:Q9QYC1

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