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ENOX1 ecto-NOX disulfide-thiol exchanger 1 [ Homo sapiens (human) ]

Gene ID: 55068, updated on 5-Mar-2024

Summary

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Official Symbol
ENOX1provided by HGNC
Official Full Name
ecto-NOX disulfide-thiol exchanger 1provided by HGNC
Primary source
HGNC:HGNC:25474
See related
Ensembl:ENSG00000120658 MIM:610914; AllianceGenome:HGNC:25474
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CNOX; PIG38; cCNOX; bA64J21.1
Summary
The protein encoded by this gene is involved in plasma membrane electron transport pathways. The encoded protein has both a hydroquinone (NADH) oxidase activity and a protein disulfide-thiol interchange activity. The two activities cycle with a periodicity of 24 minutes, with one activity being at its peak when the other is at its lowest. [provided by RefSeq, Dec 2016]
Expression
Broad expression in testis (RPKM 1.9), brain (RPKM 1.3) and 19 other tissues See more
Orthologs
mouse all
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Genomic context

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Location:
13q14.11
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (43213130..43786972, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (42431573..43005924, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (43787266..44361108, complement)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member C15 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:43693053-43693554 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:43693555-43694054 Neighboring gene long intergenic non-protein coding RNA 400 Neighboring gene LINC00400 intron CAGE-defined mid-level expression enhancer Neighboring gene NANOG hESC enhancer GRCh37_chr13:43765633-43766138 Neighboring gene molybdenum cofactor synthesis 3 pseudogene 2 Neighboring gene NANOG hESC enhancer GRCh37_chr13:43844306-43844807 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7668 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7669 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr13:43933647-43934232 Neighboring gene ribosomal protein L36 pseudogene 19 Neighboring gene ENOX1 antisense RNA 2 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr13:44196698-44197897 Neighboring gene Sharpr-MPRA regulatory region 7351 Neighboring gene uncharacterized LOC124903166 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5302 Neighboring gene coiled-coil domain containing 122 Neighboring gene laccase domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. A candidate gene for autoimmune myasthenia gravis. Landouré G, et al. Neurology, 2012 Jul 24. PMID 22744667, Free PMC Article
  2. Molecular cloning and characterization of a candidate human growth-related and time-keeping constitutive cell surface hydroquinone (NADH) oxidase. Jiang Z, et al. Biochemistry, 2008 Dec 30. PMID 19055324
  3. Multiple proteins with single activities or a single protein with multiple activities: the conundrum of cell surface NADH oxidoreductases. Scarlett DJ, et al. Biochim Biophys Acta, 2005 Jun 1. PMID 15882838
  4. A drug-unresponsive and protease-resistant CNOX protein from human sera. Sedlak D, et al. Arch Biochem Biophys, 2001 Feb 1. PMID 11360993
  5. Clinical Significance of Serum Kallistatin and ENOX1 Levels in Patients with Coronary Heart Disease. Zhang R, et al. Med Princ Pract, 2021. PMID 32712615, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Clinical Significance of Serum Kallistatin and ENOX1 Levels in Patients with Coronary Heart Disease.
    Title: Clinical Significance of Serum Kallistatin and ENOX1 Levels in Patients with Coronary Heart Disease.
  2. We verified that NRF-1 positively regulates FAM134C and ENOX1, and negatively regulates C3orf10 in human neuroblastoma IMR-32 cells and primary rat cortical neurons.
    Title: Novel genes FAM134C, C3orf10 and ENOX1 are regulated by NRF-1 and differentially regulate neurite outgrowth in neuroblastoma cells and hippocampal neurons.
  3. These results indicate that this sequence variant in ENOX1 may contribute to the familial autoimmune myasthenia in these patients.
    Title: A candidate gene for autoimmune myasthenia gravis.
  4. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
  5. copper-binding capacity, enzymatic activity, and time-keeping (clock) properties
    Title: Molecular cloning and characterization of a candidate human growth-related and time-keeping constitutive cell surface hydroquinone (NADH) oxidase.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.
EBI GWAS Catalog
Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis.
EBI GWAS Catalog
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ10094, FLJ30915

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables NADH dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables NADH dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein disulfide isomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein disulfide isomerase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in ultradian rhythm IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
  

General protein information

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Preferred Names
ecto-NOX disulfide-thiol exchanger 1
Names
candidate growth-related and time keeping constitutive hydroquinone (NADH) oxidase
candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase
cell proliferation-inducing gene 38 protein
constitutive Ecto-NOX
ecto-NADPH oxidase disulfide-thiol exchanger 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_052843.1 RefSeqGene

    Range
    5009..578851
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001127615.3 → NP_001121087.1  ecto-NOX disulfide-thiol exchanger 1 isoform b

    See identical proteins and their annotated locations for NP_001121087.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 10. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 1-9 all encode the same isoform (b).
    Source sequence(s)
    AL136959, AL138823, AL161714, AL607148, AL627430
    Consensus CDS
    CCDS9389.1
    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8
    Conserved Domains (2) summary
    TIGR02168
    Location:235 → 582
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd12228
    Location:136 → 219
    RRM_ENOX; RNA recognition motif (RRM) found in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins

  2. NM_001242863.3 → NP_001229792.1  ecto-NOX disulfide-thiol exchanger 1 isoform b

    See identical proteins and their annotated locations for NP_001229792.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 10. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 1-9 all encode the same isoform (b).
    Source sequence(s)
    AL136959, AL138823, AL161714, AL162713, AL607148, AL627430
    Consensus CDS
    CCDS9389.1
    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8
    Conserved Domains (2) summary
    TIGR02168
    Location:235 → 582
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd12228
    Location:136 → 219
    RRM_ENOX; RNA recognition motif (RRM) found in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins

  3. NM_001347963.2 → NP_001334892.1  ecto-NOX disulfide-thiol exchanger 1 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) encodes the longest isoform (a).
    Source sequence(s)
    AL138823, AL161714, AL162713, AL607148, AL627430

  4. NM_001347964.2 → NP_001334893.1  ecto-NOX disulfide-thiol exchanger 1 isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 10. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 1-9 all encode the same isoform (b).
    Source sequence(s)
    AL136959, AL138823, AL161714, AL162713, AL607148, AL627430
    Consensus CDS
    CCDS9389.1
    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8
    Conserved Domains (2) summary
    TIGR02168
    Location:235 → 582
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd12228
    Location:136 → 219
    RRM_ENOX; RNA recognition motif (RRM) found in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins

  5. NM_001347965.2 → NP_001334894.1  ecto-NOX disulfide-thiol exchanger 1 isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and coding sequence compared to variant 10. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 1-9 all encode the same isoform (b).
    Source sequence(s)
    AL136959, AL138823, AL162713, AL607148, AL627430
    Consensus CDS
    CCDS9389.1
    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8
    Conserved Domains (2) summary
    TIGR02168
    Location:235 → 582
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd12228
    Location:136 → 219
    RRM_ENOX; RNA recognition motif (RRM) found in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins

  6. NM_001347966.2 → NP_001334895.1  ecto-NOX disulfide-thiol exchanger 1 isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and coding sequence compared to variant 10. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 1-9 all encode the same isoform (b).
    Source sequence(s)
    AL136959, AL138823, AL161714, AL162713, AL607148, AL627430
    Consensus CDS
    CCDS9389.1
    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8
    Conserved Domains (2) summary
    TIGR02168
    Location:235 → 582
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd12228
    Location:136 → 219
    RRM_ENOX; RNA recognition motif (RRM) found in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins

  7. NM_001347967.2 → NP_001334896.1  ecto-NOX disulfide-thiol exchanger 1 isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR and coding sequence compared to variant 10. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 1-9 all encode the same isoform (b).
    Source sequence(s)
    AL138823, AL161714, AL162713, AL607148, AL627430
    Consensus CDS
    CCDS9389.1
    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8
    Conserved Domains (2) summary
    TIGR02168
    Location:235 → 582
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd12228
    Location:136 → 219
    RRM_ENOX; RNA recognition motif (RRM) found in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins

  8. NM_001347968.2 → NP_001334897.1  ecto-NOX disulfide-thiol exchanger 1 isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR and coding sequence compared to variant 10. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 1-9 all encode the same isoform (b).
    Source sequence(s)
    AL136959, AL138823, AL161714, AL162713, AL607148, AL627430
    Consensus CDS
    CCDS9389.1
    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8
    Conserved Domains (2) summary
    TIGR02168
    Location:235 → 582
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd12228
    Location:136 → 219
    RRM_ENOX; RNA recognition motif (RRM) found in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins

  9. NM_001347969.2 → NP_001334898.1  ecto-NOX disulfide-thiol exchanger 1 isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR and coding sequence compared to variant 10. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 1-9 all encode the same isoform (b).
    Source sequence(s)
    AL136959, AL138823, AL161714, AL162713, AL607148, AL627430
    Consensus CDS
    CCDS9389.1
    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8
    Related
    ENSP00000509229.1, ENST00000690772.1
    Conserved Domains (2) summary
    TIGR02168
    Location:235 → 582
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd12228
    Location:136 → 219
    RRM_ENOX; RNA recognition motif (RRM) found in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins

  10. NM_001347970.2 → NP_001334899.1  ecto-NOX disulfide-thiol exchanger 1 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) differs in the 5' UTR and coding sequence compared to variant 10. The resulting isoform (c) is shorter at the N-terminus compared to isoform a. Variants 11 and 12 both encode the same isoform (c).
    Source sequence(s)
    AL136959, AL138823, AL161714, AL162713, AL607148, AL627430
    Conserved Domains (2) summary
    cd12228
    Location:97 → 180
    RRM_ENOX; RNA recognition motif (RRM) in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins
    TIGR02168
    Location:222 → 543
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  11. NM_001347971.2 → NP_001334900.1  ecto-NOX disulfide-thiol exchanger 1 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12) differs in the 5' UTR and coding sequence compared to variant 10. The resulting isoform (c) is shorter at the N-terminus compared to isoform a. Variants 11 and 12 both encode the same isoform (c).
    Source sequence(s)
    AL136959, AL138823, AL161714, AL162713, AL607148, AL627430
    Conserved Domains (2) summary
    cd12228
    Location:97 → 180
    RRM_ENOX; RNA recognition motif (RRM) in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins
    TIGR02168
    Location:222 → 543
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  12. NM_017993.5 → NP_060463.2  ecto-NOX disulfide-thiol exchanger 1 isoform b

    See identical proteins and their annotated locations for NP_060463.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) differs in the 5' UTR and coding sequence compared to variant 10. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 1-9 all encode the same isoform (b).
    Source sequence(s)
    AL136959, AL138823, AL161714, AL162713, AL607148, AL627430
    Consensus CDS
    CCDS9389.1
    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8
    Related
    ENSP00000261488.6, ENST00000261488.10
    Conserved Domains (2) summary
    TIGR02168
    Location:235 → 582
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd12228
    Location:136 → 219
    RRM_ENOX; RNA recognition motif (RRM) found in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins

RNA

  1. NR_145132.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AL162713

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    43213130..43786972 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047430424.1 → XP_047286380.1  ecto-NOX disulfide-thiol exchanger 1 isoform X2

  2. XM_047430426.1 → XP_047286382.1  ecto-NOX disulfide-thiol exchanger 1 isoform X2

  3. XM_011535127.4 → XP_011533429.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    See identical proteins and their annotated locations for XP_011533429.1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8
    Conserved Domains (2) summary
    TIGR02168
    Location:235 → 582
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd12228
    Location:136 → 219
    RRM_ENOX; RNA recognition motif (RRM) found in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins

  4. XM_024449373.2 → XP_024305141.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8
    Conserved Domains (2) summary
    TIGR02168
    Location:235 → 582
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd12228
    Location:136 → 219
    RRM_ENOX; RNA recognition motif (RRM) found in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins

  5. XM_047430427.1 → XP_047286383.1  ecto-NOX disulfide-thiol exchanger 1 isoform X2

  6. XM_047430425.1 → XP_047286381.1  ecto-NOX disulfide-thiol exchanger 1 isoform X2

  7. XM_047430421.1 → XP_047286377.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  8. XM_047430422.1 → XP_047286378.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  9. XM_047430417.1 → XP_047286373.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  10. XM_047430419.1 → XP_047286375.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  11. XM_047430418.1 → XP_047286374.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  12. XM_047430420.1 → XP_047286376.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  13. XM_047430416.1 → XP_047286372.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  14. XM_047430423.1 → XP_047286379.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  15. XM_024449374.2 → XP_024305142.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8
    Conserved Domains (2) summary
    TIGR02168
    Location:235 → 582
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd12228
    Location:136 → 219
    RRM_ENOX; RNA recognition motif (RRM) found in the cell surface Ecto-NOX disulfide-thiol exchanger (ECTO-NOX or ENOX) proteins

  16. XM_047430428.1 → XP_047286384.1  ecto-NOX disulfide-thiol exchanger 1 isoform X3

  17. XM_047430429.1 → XP_047286385.1  ecto-NOX disulfide-thiol exchanger 1 isoform X4

  18. XM_047430430.1 → XP_047286386.1  ecto-NOX disulfide-thiol exchanger 1 isoform X5

    UniProtKB/TrEMBL
    A0A0S2Z5N4

RNA

  1. XR_007063686.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    42431573..43005924 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054374644.1 → XP_054230619.1  ecto-NOX disulfide-thiol exchanger 1 isoform X2

  2. XM_054374646.1 → XP_054230621.1  ecto-NOX disulfide-thiol exchanger 1 isoform X2

  3. XM_054374635.1 → XP_054230610.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  4. XM_054374634.1 → XP_054230609.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  5. XM_054374647.1 → XP_054230622.1  ecto-NOX disulfide-thiol exchanger 1 isoform X2

  6. XM_054374645.1 → XP_054230620.1  ecto-NOX disulfide-thiol exchanger 1 isoform X2

  7. XM_054374640.1 → XP_054230615.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  8. XM_054374639.1 → XP_054230614.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  9. XM_054374637.1 → XP_054230612.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  10. XM_054374636.1 → XP_054230611.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  11. XM_054374643.1 → XP_054230618.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  12. XM_054374638.1 → XP_054230613.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  13. XM_054374641.1 → XP_054230616.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  14. XM_054374642.1 → XP_054230617.1  ecto-NOX disulfide-thiol exchanger 1 isoform X1

    UniProtKB/Swiss-Prot
    A4GU15, A6NMH9, B7Z5K1, Q2TU81, Q5VT11, Q8TC92, Q9NWE0
    UniProtKB/TrEMBL
    A0A024RDT8

  15. XM_054374648.1 → XP_054230623.1  ecto-NOX disulfide-thiol exchanger 1 isoform X3

  16. XM_054374649.1 → XP_054230624.1  ecto-NOX disulfide-thiol exchanger 1 isoform X4

  17. XM_054374650.1 → XP_054230625.1  ecto-NOX disulfide-thiol exchanger 1 isoform X5

    UniProtKB/TrEMBL
    A0A0S2Z5N4

RNA

  1. XR_008488768.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8TC92.1 GenPept UniProtKB/Swiss-Prot:Q8TC92

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