snx6 sorting nexin 6 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: snx6provided by ZNC
Official Full Name: sorting nexin 6provided by ZNC
Primary source: ZFIN:ZDB-GENE-050913-152
See related: Ensembl:ENSDARG00000058444 AllianceGenome:ZFIN:ZDB-GENE-050913-152
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fa55b10; im:7146294; wu:fa55b10; zgc:110798
Summary: Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in retrograde transport, endosome to Golgi. Predicted to act upstream of or within intracellular protein transport. Predicted to be active in endosome. Orthologous to human SNX6 (sorting nexin 6). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (9963431..9995785, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (9807387..9839756, complement)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fa55b10.s1 (e-PCR)
- UniSTS:202525

fj84c07.y1 (e-PCR)
- UniSTS:200073

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables phosphatidylinositol binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within intracellular protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
involved_in retrograde transport, endosome to Golgi	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in endosome	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: sorting nexin-6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001030217.2 → NP_001025388.2 sorting nexin-6

Status: VALIDATED

Source sequence(s)

CU463180

UniProtKB/TrEMBL

A0A8M1N7C5, F8W5C6

Related

ENSDARP00000123712.1, ENSDART00000148463.3

Conserved Domains (2) summary

cd07292
Location:31 → 171

PX_SNX6; The phosphoinositide binding Phox Homology domain of Sorting Nexin 6

cd07662
Location:187 → 404

BAR_SNX6; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 6