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smarcc2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 [ Danio rerio (zebrafish) ]

Gene ID: 567476, updated on 11-Apr-2024

Summary

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Official Symbol
smarcc2provided by ZNC
Official Full Name
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-100728-1
See related
Ensembl:ENSDARG00000077946 AllianceGenome:ZFIN:ZDB-GENE-100728-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
baf170
Summary
Predicted to enable histone binding activity. Predicted to be involved in positive regulation of transcription, DNA-templated. Predicted to be part of SWI/SNF complex; nBAF complex; and npBAF complex. Orthologous to human SMARCC2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
26
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (39836453..39866673)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (39838942..39867956)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene phosphofructokinase, muscle b Neighboring gene complement component 1, q subcomponent-like 4b Neighboring gene myosin, light chain 6, alkali, smooth muscle and non-muscle Neighboring gene Ts translation elongation factor, mitochondrial

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Abrogation of Stem Loop Binding Protein (Slbp) function leads to a failure of cells to transition from proliferation to differentiation, retinal coloboma and midline axon guidance deficits. Turner KJ, et al. PLoS One, 2019. PMID 30695021, Free PMC Article
  2. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
  3. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in positive regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of SWI/SNF complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of nBAF complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of npBAF complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SWI/SNF complex subunit SMARCC2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    39836453..39866673
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_690772.7 → XP_695864.3  SWI/SNF complex subunit SMARCC2

    UniProtKB/TrEMBL
    A0A8M9Q5E9, E7FFZ4
    Related
    ENSDARP00000099015.2, ENSDART00000112637.4
    Conserved Domains (4) summary
    pfam16495
    Location:872 → 938
    SWIRM-assoc_1; SWIRM-associated region 1
    pfam16496
    Location:4 → 418
    SWIRM-assoc_2; SWIRM-associated domain at the N-terminal
    cl26511
    Location:754 → 935
    Neuromodulin_N; Gap junction protein N-terminal region
    cl27154
    Location:380 → 726
    SWIRM; SWIRM domain

Reference GRCz11 ALT_DRER_TU_3

Genomic

  1. NW_018395382.1 Reference GRCz11 ALT_DRER_TU_3

    Range
    182702..214192
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021474611.1 → XP_021330286.1  SWI/SNF complex subunit SMARCC2

    UniProtKB/TrEMBL
    A0A8M9Q5E9, E7FFZ4
    Conserved Domains (4) summary
    pfam16495
    Location:872 → 938
    SWIRM-assoc_1; SWIRM-associated region 1
    pfam16496
    Location:4 → 418
    SWIRM-assoc_2; SWIRM-associated domain at the N-terminal
    cl26511
    Location:754 → 935
    Neuromodulin_N; Gap junction protein N-terminal region
    cl27154
    Location:380 → 726
    SWIRM; SWIRM domain
Nucleotide Protein
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