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anapc1 anaphase promoting complex subunit 1 [ Danio rerio (zebrafish) ]

Gene ID: 568795, updated on 27-Mar-2024

Summary

Official Symbol
anapc1provided by ZNC
Official Full Name
anaphase promoting complex subunit 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-081107-12
See related
Ensembl:ENSDARG00000075687 AllianceGenome:ZFIN:ZDB-GENE-081107-12
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-160m22.1
Summary
Predicted to enable molecular adaptor activity. Predicted to be involved in anaphase-promoting complex-dependent catabolic process; metaphase/anaphase transition of mitotic cell cycle; and protein K11-linked ubiquitination. Predicted to act upstream of or within cell division. Predicted to be part of anaphase-promoting complex. Human ortholog(s) of this gene implicated in Rothmund-Thomson syndrome. Orthologous to human ANAPC1 (anaphase promoting complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 13
Exon count:
48
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (47007114..47175666)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (46717291..46885829)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene F-box protein 5 Neighboring gene vasoactive intestinal peptide Neighboring gene BCL2 like 11 Neighboring gene acyl-CoA oxidase-like

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in anaphase-promoting complex-dependent catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in metaphase/anaphase transition of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein K11-linked ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of anaphase-promoting complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of anaphase-promoting complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
anaphase-promoting complex subunit 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    47007114..47175666
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005157066.3XP_005157123.1  anaphase-promoting complex subunit 1 isoform X1

    UniProtKB/TrEMBL
    A0A2R8QA59, A0A8M2B392
    Related
    ENSDARP00000150216.1, ENSDART00000183205.1
    Conserved Domains (1) summary
    pfam12859
    Location:147199
    ANAPC1; Anaphase-promoting complex subunit 1
  2. XM_005157067.3XP_005157124.1  anaphase-promoting complex subunit 1 isoform X3

    UniProtKB/TrEMBL
    A0A8M2B3F5
    Conserved Domains (1) summary
    pfam12859
    Location:147199
    ANAPC1; Anaphase-promoting complex subunit 1
  3. XM_001921133.4XP_001921168.2  anaphase-promoting complex subunit 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M1QKJ8
    Conserved Domains (1) summary
    pfam12859
    Location:147205
    ANAPC1; Anaphase-promoting complex subunit 1
  4. XM_021480904.1XP_021336579.1  anaphase-promoting complex subunit 1 isoform X4

    UniProtKB/TrEMBL
    A0A8M9QG54
    Conserved Domains (1) summary
    pfam12859
    Location:147187
    ANAPC1; Anaphase-promoting complex subunit 1