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Stk32b serine/threonine kinase 32B [ Mus musculus (house mouse) ]

Gene ID: 64293, updated on 11-Apr-2024

Summary

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Official Symbol
Stk32bprovided by MGI
Official Full Name
serine/threonine kinase 32Bprovided by MGI
Primary source
MGI:MGI:1927552
See related
Ensembl:ENSMUSG00000029123 AllianceGenome:MGI:1927552
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
STKG6; Stk32; YANK2; 2510009F08Rik
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Predicted to act upstream of or within phosphorylation. Is expressed in several structures, including cranium; hindlimb; respiratory system; sensory organ; and telencephalon. Orthologous to human STK32B (serine/threonine kinase 32B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E18 (RPKM 17.1), whole brain E14.5 (RPKM 15.3) and 6 other tissues See more
Orthologs
human all
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Genomic context

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See Stk32b in Genome Data Viewer
Location:
5 B3; 5 20.18 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (37604169..37874503, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (37446825..37717153, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene 42935 Neighboring gene EvC ciliary complex subunit 1 Neighboring gene STARR-seq mESC enhancer starr_12901 Neighboring gene EvC ciliary complex subunit 2 Neighboring gene predicted gene 15732 Neighboring gene STARR-seq mESC enhancer starr_12902 Neighboring gene STARR-seq mESC enhancer starr_12903 Neighboring gene STARR-seq mESC enhancer starr_12904 Neighboring gene cytokine-like 1 Neighboring gene predicted gene, 40286

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental dysostosis. Ruiz-Perez VL, et al. Nat Genet, 2000 Mar. PMID 10700184
  2. Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus. Rattner A, et al. Elife, 2020 Oct 21. PMID 33084572, Free PMC Article
  3. A mouse knockout library for secreted and transmembrane proteins. Tang T, et al. Nat Biotechnol, 2010 Jul. PMID 20562862
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
serine/threonine-protein kinase 32B
Names
serine threonine kinase 32
NP_071861.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022416.3 → NP_071861.1  serine/threonine-protein kinase 32B

    See identical proteins and their annotated locations for NP_071861.1

    Status: VALIDATED

    Source sequence(s)
    AC110244, AC110565, AC158588
    Consensus CDS
    CCDS39076.1
    UniProtKB/Swiss-Prot
    Q7TMD3, Q8C4E0, Q9JJX8
    Related
    ENSMUSP00000092432.5, ENSMUST00000094836.6
    Conserved Domains (2) summary
    smart00220
    Location:23 → 272
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05578
    Location:22 → 283
    STKc_Yank1; Catalytic domain of the Serine/Threonine Kinase, Yank1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    37604169..37874503 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9JJX8.2 GenPept UniProtKB/Swiss-Prot:Q9JJX8

Gene LinkOut

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