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C8orf33 chromosome 8 open reading frame 33 [ Homo sapiens (human) ]

Gene ID: 65265, updated on 7-Apr-2024

Summary

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Official Symbol
C8orf33provided by HGNC
Official Full Name
chromosome 8 open reading frame 33provided by HGNC
Primary source
HGNC:HGNC:26104
See related
Ensembl:ENSG00000182307 AllianceGenome:HGNC:26104
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in adrenal (RPKM 26.3), ovary (RPKM 21.4) and 25 other tissues See more
Orthologs
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Genomic context

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Location:
8q24.3
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (145052467..145056030)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (146229380..146234031)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (146277853..146281416)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene endogenous retrovirus group K member 6 Env polyprotein-like Neighboring gene zinc finger with KRAB and SCAN domains 8 pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28112 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28113 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19718 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:146278427-146279227

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF). Zhao J, et al. J Proteomics, 2011 Dec 21. PMID 21907836
  2. MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation. Seo G, et al. Cell Rep, 2020 Jul 7. PMID 32640226, Free PMC Article
  3. The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival. He Y, et al. J Biol Chem, 2020 Feb 14. PMID 31822558, Free PMC Article
  4. IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5. Zhang J, et al. J Proteome Res, 2020 Mar 6. PMID 31950832, Free PMC Article
  5. An empirical framework for binary interactome mapping. Venkatesan K, et al. Nat Methods, 2009 Jan. PMID 19060904, Free PMC Article

See all (52) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ20989

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
UPF0488 protein C8orf33

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023080.3 → NP_075568.1  UPF0488 protein C8orf33

    See identical proteins and their annotated locations for NP_075568.1

    Status: VALIDATED

    Source sequence(s)
    BC010001, DA467518
    Consensus CDS
    CCDS34974.1
    UniProtKB/Swiss-Prot
    A6NGC0, Q96BT8, Q9H7E9
    UniProtKB/TrEMBL
    A0A3B3IRR6
    Related
    ENSP00000330361.6, ENST00000331434.7
    Conserved Domains (1) summary
    pfam15393
    Location:116 → 228
    DUF4615; Domain of unknown function (DUF4615)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    145052467..145056030
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791783.1 Reference GRCh38.p14 PATCHES

    Range
    9908..13471
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    146229380..146234031
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054361025.1 → XP_054217000.1  UPF0488 protein C8orf33 isoform X1

    UniProtKB/Swiss-Prot
    A6NGC0, Q96BT8, Q9H7E9
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9H7E9.1 GenPept UniProtKB/Swiss-Prot:Q9H7E9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
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