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ST2 suppression of tumorigenicity 2 [ Homo sapiens (human) ]

Gene ID: 6761, updated on 4-Jan-2024

Summary

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Gene symbol
ST2
Gene description
suppression of tumorigenicity 2
Primary source
MIM:185440
Gene type
unknown
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Annotation information
Note: This region (ST2; GeneID: 6761) on chromosome 11 represents a putative locus that is associated with various forms of cancer. It has been confused in the published literature with the IL1RL1 gene (GeneID: 9173), which has the alias ST2, on chromosome 2. IL1RL1 encodes a member of the interleukin 1 receptor family. [23 Jun 2016]

Genomic context

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Location:
11p14.3-p12

Bibliography

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Related articles in PubMed

  1. Plasma Soluble ST2 Levels Are Higher in Neurodegenerative Disorders and Associated with Poorer Cognition. Tan YJ, et al. J Alzheimers Dis, 2023. PMID 36776067
  2. Soluble ST2 as a New Oxidative Stress and Inflammation Marker in Metabolic Syndrome. Roy I, et al. Int J Environ Res Public Health, 2023 Jan 31. PMID 36767947, Free PMC Article
  3. Suppression of Tumorigenicity 2 Pro-Inflammatory Biomarker Linking Diabetes Mellitus and Periodontitis: A Pilot Study. Navya PD, et al. Med Sci Monit, 2022 Nov 15. PMID 36377211, Free PMC Article
  4. Effect of β-Blocker Therapy on the Level of Soluble ST2 Protein in Pediatric Dilated Cardiomyopathy. Jiao M, et al. Medicina (Kaunas), 2022 Sep 23. PMID 36295500, Free PMC Article
  5. Clinical and prognostic relevance of sST2 in adults with dengue-associated cardiac impairment and severe dengue. Teo A, et al. PLoS Negl Trop Dis, 2022 Oct. PMID 36228040, Free PMC Article

See all (142) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Modulation of Neuroinflammation: Advances in Roles and Mechanisms of the IL-33/ST2 Axis Involved in Ischemic Stroke.
    Title: Modulation of Neuroinflammation: Advances in Roles and Mechanisms of the IL-33/ST2 Axis Involved in Ischemic Stroke.
  2. Serum levels of soluble suppression of tumorigenicity 2 (sST2) and heart-type fatty acid binding protein (H-FABP) independently predict in-hospital mortality in geriatric patients with COVID-19.
    Title: Serum levels of soluble suppression of tumorigenicity 2 (sST2) and heart-type fatty acid binding protein (H-FABP) independently predict in-hospital mortality in geriatric patients with COVID-19.
  3. Exploring the significance of interleukin-33/ST2 axis in minimal change disease.
    Title: Exploring the significance of interleukin-33/ST2 axis in minimal change disease.
  4. Galectin-3 and suppression of tumorigenicity 2: Two emerging cardiac biomarkers that may be predictors of cardiac fibrosis development in sport.
    Title: Galectin-3 and suppression of tumorigenicity 2: Two emerging cardiac biomarkers that may be predictors of cardiac fibrosis development in sport.
  5. The association of serum IL-33/ST2 expression with hepatocellular carcinoma.
    Title: The association of serum IL-33/ST2 expression with hepatocellular carcinoma.
  6. Interleukin-33 and Soluble ST2 Levels in Infants with Hypoxic-Ischemic Encephalopathy.
    Title: Interleukin-33 and Soluble ST2 Levels in Infants with Hypoxic-Ischemic Encephalopathy.
  7. IL-33/ST2 axis of human amnion fibroblasts participates in inflammatory reactions at parturition.
    Title: IL-33/ST2 axis of human amnion fibroblasts participates in inflammatory reactions at parturition.
  8. Interleukin-33 and soluble suppression of tumorigenicity 2 in scleroderma cardiac involvement.
    Title: Interleukin-33 and soluble suppression of tumorigenicity 2 in scleroderma cardiac involvement.
  9. Differential Expression of Caveolin-3, Suppression of Tumorigenicity 2, and Growth Differentiation Factor-15 Genes and Their Association with Acute Myocardial Infarction: A Cross-Sectional Study in a Multi-Specialty Hospital in Tamil Nadu.
    Title: Differential Expression of Caveolin-3, Suppression of Tumorigenicity 2, and Growth Differentiation Factor-15 Genes and Their Association with Acute Myocardial Infarction: A Cross-Sectional Study in a Multi-Specialty Hospital in Tamil Nadu.
  10. The IL-33:ST2 axis is unlikely to play a central fibrogenic role in idiopathic pulmonary fibrosis.
    Title: The IL-33:ST2 axis is unlikely to play a central fibrogenic role in idiopathic pulmonary fibrosis.
Submit: New GeneRIF Correction See all GeneRIFs (144)

Phenotypes

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suppression of tumorigenicity 2

General gene information

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