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TMEM78 transmembrane protein 78 [ Homo sapiens (human) ]

Gene ID: 677790, updated on 10-Oct-2023

Summary

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Official Symbol
TMEM78provided by HGNC
Official Full Name
transmembrane protein 78provided by HGNC
Primary source
HGNC:HGNC:32307
See related
Ensembl:ENSG00000177800 AllianceGenome:HGNC:32307
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
1q42.13
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (229249636..229251810)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (228628312..228630486)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (229385383..229387557)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:229194589-229195089 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:229195717-229196216 Neighboring gene iron-sulfur cluster assembly 1 pseudogene 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:229223803-229224521 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:229227240-229228172 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:229228173-229229104 Neighboring gene long intergenic non-protein coding RNA 2815 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:229243991-229244514 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:229244515-229245036 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:229251653-229252154 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:229252155-229252654 Neighboring gene Sharpr-MPRA regulatory region 2560 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:229295511-229296011 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:229297904-229298404 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:229298405-229298905 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:229309691-229310255 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:229313110-229314036 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:229314037-229314963 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:229314964-229315890 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2699 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:229333469-229333968 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:229338935-229339572 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:229341375-229341982 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:229356687-229357188 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:229357189-229357688 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:229360637-229361210 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:229363801-229364526 Neighboring gene Sharpr-MPRA regulatory region 11146 Neighboring gene uncharacterized LOC102723935 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:229388645-229389519 Neighboring gene uncharacterized LOC124904540 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr1:229389520-229390393 Neighboring gene RAB4A antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1925 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1926 Neighboring gene RAB4A, member RAS oncogene family

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition. Benslimane Y, et al. Aging Cell, 2021 Apr. PMID 33660365, Free PMC Article
  2. The DNA sequence and biological annotation of human chromosome 1. Gregory SG, et al. Nature, 2006 May 18. PMID 16710414
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Clone Names

  • FLJ40168

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_172940.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL162595
    Related
    ENST00000323223.2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    229249636..229251810
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    228628312..228630486
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001040079.1: Suppressed sequence

    Description
    NM_001040079.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5T7P6.1 GenPept UniProtKB/Swiss-Prot:Q5T7P6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
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Research Materials
Miscellaneous