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Fcamr Fc alpha and mu receptor [ Rattus norvegicus (Norway rat) ]

Gene ID: 681070, updated on 3-Apr-2024

Summary

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Official Symbol
Fcamrprovided by RGD
Official Full Name
Fc alpha and mu receptorprovided by RGD
Primary source
RGD:1584674
See related
Ensembl:ENSRNOG00000004393 AllianceGenome:RGD:1584674
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable IgA binding activity; IgM binding activity; and transmembrane signaling receptor activity. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human FCAMR (Fc fragment of IgA and IgM receptor). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 13.5), Kidney (RPKM 7.3) and 4 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Fcamr in Genome Data Viewer
Location:
13q13
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (44825931..44839938)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (42273891..42288002)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (47538052..47552370)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene similar to human chromosome 1 open reading frame 116 Neighboring gene YOD1 deubiquitinase Neighboring gene polymeric immunoglobulin receptor Neighboring gene Fc mu receptor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes. Shibuya A, et al. Nat Immunol, 2000 Nov. PMID 11062505
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables IgA binding ISO
Inferred from Sequence Orthology
more info
  
enables IgM binding ISO
Inferred from Sequence Orthology
more info
  
enables transmembrane signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane signaling receptor activity ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
high affinity immunoglobulin alpha and immunoglobulin mu Fc receptor
Names
Fc fragment of IgA and IgM receptor
Fc receptor, IgA, IgM, high affinity

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    44825931..44839938
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063272678.1 → XP_063128748.1  high affinity immunoglobulin alpha and immunoglobulin mu Fc receptor

    UniProtKB/TrEMBL
    A6IC03, D4A1M4
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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