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Anapc13 anaphase promoting complex subunit 13 [ Rattus norvegicus (Norway rat) ]

Gene ID: 685029, updated on 2-May-2024

Summary

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Official Symbol
Anapc13provided by RGD
Official Full Name
anaphase promoting complex subunit 13provided by RGD
Primary source
RGD:1583270
See related
Ensembl:ENSRNOG00000008459 AllianceGenome:RGD:1583270
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in protein K11-linked ubiquitination. Predicted to be part of anaphase-promoting complex. Orthologous to human ANAPC13 (anaphase promoting complex subunit 13). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 96.9), Heart (RPKM 96.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
8q32
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (112084405..112092821)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (103205520..103213936)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (111107358..111115774)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene kyphoscoliosis peptidase Neighboring gene ribosomal protein L27, pseudogene 3 Neighboring gene centrosomal protein 63 Neighboring gene uncharacterized LOC134480096 Neighboring gene angiomotin like 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex. Jin L, et al. Cell, 2008 May 16. PMID 18485873, Free PMC Article
  2. Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. Dube P, et al. Mol Cell, 2005 Dec 22. PMID 16364912
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in anaphase-promoting complex-dependent catabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in protein K11-linked ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein K11-linked ubiquitination ISO
Inferred from Sequence Orthology
more info
  
involved_in protein K48-linked ubiquitination ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of anaphase-promoting complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of anaphase-promoting complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
anaphase-promoting complex subunit 13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001173983.3 → NP_001167454.1  anaphase-promoting complex subunit 13

    See identical proteins and their annotated locations for NP_001167454.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    A6I2H8, D4A427
    Related
    ENSRNOP00000011203.2, ENSRNOT00000011203.5
    Conserved Domains (1) summary
    pfam05839
    Location:1 → 74
    Apc13p; Apc13p protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    112084405..112092821
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006243681.5 → XP_006243743.1  anaphase-promoting complex subunit 13 isoform X1

    See identical proteins and their annotated locations for XP_006243743.1

    UniProtKB/TrEMBL
    A6I2H8, D4A427
    Conserved Domains (1) summary
    pfam05839
    Location:1 → 74
    Apc13p; Apc13p protein

  2. XM_039082157.2 → XP_038938085.1  anaphase-promoting complex subunit 13 isoform X1

    UniProtKB/TrEMBL
    A6I2H8, D4A427
    Conserved Domains (1) summary
    pfam05839
    Location:1 → 74
    Apc13p; Apc13p protein
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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