A4gnt alpha-1,4-N-acetylglucosaminyltransferase [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: A4gntprovided by RGD
Official Full Name: alpha-1,4-N-acetylglucosaminyltransferaseprovided by RGD
Primary source: RGD:1590210
See related: Ensembl:ENSRNOG00000042649 AllianceGenome:RGD:1590210
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable acetylglucosaminyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to act upstream of or within glycoprotein biosynthetic process and negative regulation of epithelial cell proliferation. Predicted to be located in Golgi membrane. Orthologous to human A4GNT (alpha-1,4-N-acetylglucosaminyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Spleen (RPKM 2.8), Thymus (RPKM 2.4) and 2 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q31

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (109050362..109058539)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (100172038..100179218)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (107856853..107866438)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables acetylglucosaminyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables acetylglucosaminyltransferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
acts_upstream_of epithelial cell proliferation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within glycoprotein biosynthetic process	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within negative regulation of epithelial cell proliferation	ISO Inferred from Sequence Orthology more info
involved_in protein O-linked glycosylation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein O-linked glycosylation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: alpha-1,4-N-acetylglucosaminyltransferase

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001426915.1 → NP_001413844.1 alpha-1,4-N-acetylglucosaminyltransferase

Status: VALIDATED

Source sequence(s)

JAXUCZ010000008

UniProtKB/TrEMBL

A6I2E1, D3ZG90