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Znf740 zinc finger protein 740 [ Rattus norvegicus (Norway rat) ]

Gene ID: 685834, updated on 5-Mar-2024

Summary

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Official Symbol
Znf740provided by RGD
Official Full Name
zinc finger protein 740provided by RGD
Primary source
RGD:1589052
See related
Ensembl:ENSRNOG00000012192 AllianceGenome:RGD:1589052
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Orthologous to human ZNF740 (zinc finger protein 740). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 176.4), Kidney (RPKM 159.9) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Znf740 in Genome Data Viewer
Location:
7q36
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (135215413..135226189)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (133337038..133347594)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (143810033..143820459)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene insulin-like growth factor binding protein 6 Neighboring gene sterol O-acyltransferase 2 Neighboring gene cysteine sulfinic acid decarboxylase Neighboring gene integrin subunit beta 7 Neighboring gene uncharacterized LOC134479582 Neighboring gene retinoic acid receptor, gamma Neighboring gene uncharacterized LOC134479581

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 740

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    135215413..135226189
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063264457.1 → XP_063120527.1  zinc finger protein 740 isoform X5

  2. XM_008765873.3 → XP_008764095.1  zinc finger protein 740 isoform X5

    See identical proteins and their annotated locations for XP_008764095.1

    UniProtKB/TrEMBL
    D4A538
    Conserved Domains (2) summary
    sd00017
    Location:90 → 110
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:102 → 127
    zf-H2C2_2; Zinc-finger double domain

  3. XM_006242455.4 → XP_006242517.1  zinc finger protein 740 isoform X1

    See identical proteins and their annotated locations for XP_006242517.1

    UniProtKB/TrEMBL
    A0A8I5ZWP1, D4A538
    Related
    ENSRNOP00000083176.1, ENSRNOT00000114738.1
    Conserved Domains (2) summary
    sd00017
    Location:115 → 135
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:127 → 152
    zf-H2C2_2; Zinc-finger double domain

  4. XM_008765871.3 → XP_008764093.1  zinc finger protein 740 isoform X4

    See identical proteins and their annotated locations for XP_008764093.1

    UniProtKB/TrEMBL
    D4A538
    Conserved Domains (2) summary
    sd00017
    Location:103 → 123
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:115 → 140
    zf-H2C2_2; Zinc-finger double domain

  5. XM_063264458.1 → XP_063120528.1  zinc finger protein 740 isoform X7

  6. XM_008765870.3 → XP_008764092.1  zinc finger protein 740 isoform X2

    See identical proteins and their annotated locations for XP_008764092.1

    UniProtKB/TrEMBL
    D4A538
    Related
    ENSRNOP00000016240.6, ENSRNOT00000016240.8
    Conserved Domains (2) summary
    sd00017
    Location:115 → 135
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:127 → 152
    zf-H2C2_2; Zinc-finger double domain

  7. XM_006242458.4 → XP_006242520.1  zinc finger protein 740 isoform X3

    See identical proteins and their annotated locations for XP_006242520.1

    UniProtKB/TrEMBL
    D4A538
    Conserved Domains (2) summary
    sd00017
    Location:103 → 123
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:115 → 140
    zf-H2C2_2; Zinc-finger double domain

  8. XM_008765875.3 → XP_008764097.1  zinc finger protein 740 isoform X6

    See identical proteins and their annotated locations for XP_008764097.1

    Conserved Domains (2) summary
    sd00017
    Location:65 → 85
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:77 → 102
    zf-H2C2_2; Zinc-finger double domain

  9. XM_039080395.1 → XP_038936323.1  zinc finger protein 740 isoform X8

    UniProtKB/TrEMBL
    A0A8I5ZQ97
    Related
    ENSRNOP00000080250.1, ENSRNOT00000097830.1
    Conserved Domains (2) summary
    sd00017
    Location:53 → 73
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:65 → 90
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. XR_010053536.1 RNA Sequence

  2. XR_010053537.1 RNA Sequence

Nucleotide Protein Strain
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