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Enthd1 ENTH domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 685900, updated on 19-May-2024

Summary

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Official Symbol
Enthd1provided by RGD
Official Full Name
ENTH domain containing 1provided by RGD
Primary source
RGD:1587874
See related
Ensembl:ENSRNOG00000025344 AllianceGenome:RGD:1587874
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1565081
Summary
Predicted to enable clathrin binding activity and phospholipid binding activity. Predicted to be involved in endocytosis. Predicted to be part of clathrin vesicle coat. Predicted to be active in endosome and plasma membrane. Orthologous to human ENTHD1 (ENTH domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 16.9) and Thymus (RPKM 3.7) See more
Orthologs
human mouse all
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Genomic context

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See Enthd1 in Genome Data Viewer
Location:
7q34
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (113875018..113989970, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (111994775..112109246, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (121668857..121784530, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S19 binding protein 1 Neighboring gene calcium voltage-gated channel subunit alpha1 I Neighboring gene uncharacterized LOC134479941 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene BAF nuclear assembly factor 1, pseudogene 5 Neighboring gene ribosomal protein L22 like 1, pseudogene 3 Neighboring gene GRB2-related adaptor protein 2 Neighboring gene family with sequence similarity 83, member F

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC187523

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables clathrin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of clathrin vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ENTH domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135913.1 → NP_001129385.1  ENTH domain-containing protein 1

    See identical proteins and their annotated locations for NP_001129385.1

    Status: PROVISIONAL

    Source sequence(s)
    BC167764
    UniProtKB/TrEMBL
    B3DMA3
    Related
    ENSRNOT00000034912.5
    Conserved Domains (1) summary
    pfam01417
    Location:14 → 137
    ENTH; ENTH domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    113875018..113989970 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063264270.1 → XP_063120340.1  ENTH domain-containing protein 1 isoform X2

  2. XM_063264269.1 → XP_063120339.1  ENTH domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    B3DMA3

  3. XM_063264271.1 → XP_063120341.1  ENTH domain-containing protein 1 isoform X3

  4. XM_063264272.1 → XP_063120342.1  ENTH domain-containing protein 1 isoform X4

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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