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Tbc1d12 TBC1 domain family, member 12 [ Rattus norvegicus (Norway rat) ]

Gene ID: 685933, updated on 3-Apr-2024

Summary

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Symbol
Tbc1d12provided by RGD
Full Name
TBC1 domain family, member 12provided by RGD
Primary source
RGD:9377071
See related
Ensembl:ENSRNOG00000036598 AllianceGenome:RGD:9377071
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Orthologous to human TBC1D12 (TBC1 domain family member 12). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 88.8), Adrenal (RPKM 81.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Tbc1d12 in Genome Data Viewer
Location:
1q53
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (246015985..246098241)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (236603597..236685859)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (257828474..257885689)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene phospholipase C, epsilon 1 Neighboring gene selenophosphate synthetase 1, pseudogene 1 Neighboring gene NOC3-like DNA replication regulator Neighboring gene uncharacterized LOC134483995 Neighboring gene ribosomal protein L35A like 10 Neighboring gene helicase, lymphoid specific

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in endosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
TBC1 domain family member 12
Names
TBC1 domain family member 12-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001377114.1 → NP_001364043.1  TBC1 domain family member 12

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/Swiss-Prot
    M0R7T9
    Related
    ENSRNOP00000070589.1, ENSRNOT00000078738.2
    Conserved Domains (1) summary
    pfam00566
    Location:462 → 630
    RabGAP-TBC; Rab-GTPase-TBC domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    246015985..246098241
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006231335.5 → XP_006231397.1  TBC1 domain family member 12 isoform X1

    See identical proteins and their annotated locations for XP_006231397.1

    UniProtKB/TrEMBL
    D3ZI97, M0R9H1
    Related
    ENSRNOP00000066139.2
    Conserved Domains (1) summary
    pfam00566
    Location:388 → 555
    RabGAP-TBC; Rab-GTPase-TBC domain

  2. XM_039090978.2 → XP_038946906.1  TBC1 domain family member 12 isoform X2

    UniProtKB/TrEMBL
    A6I193
    Conserved Domains (1) summary
    pfam00566
    Location:121 → 289
    RabGAP-TBC; Rab-GTPase-TBC domain

  3. XM_063273921.1 → XP_063129991.1  TBC1 domain family member 12 isoform X2

    UniProtKB/TrEMBL
    A6I193

RNA

  1. XR_005492272.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M0R7T9.1 GenPept UniProtKB/Swiss-Prot:M0R7T9

Gene LinkOut

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