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Gxylt2 glucoside xylosyltransferase 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 688618, updated on 5-Mar-2024

Summary

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Official Symbol
Gxylt2provided by RGD
Official Full Name
glucoside xylosyltransferase 2provided by RGD
Primary source
RGD:1586482
See related
Ensembl:ENSRNOG00000005621 AllianceGenome:RGD:1586482
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Glt8d4
Summary
Predicted to enable UDP-xylosyltransferase activity. Predicted to be involved in O-glycan processing. Orthologous to human GXYLT2 (glucoside xylosyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 40.6), Lung (RPKM 29.4) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Gxylt2 in Genome Data Viewer
Location:
4q34
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (134903595..135006066)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (133347230..133449708)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (133179185..133263493)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120102354 Neighboring gene SHQ1, H/ACA ribonucleoprotein assembly factor Neighboring gene actin, gamma 1, pseudogene 9 Neighboring gene uncharacterized LOC134486825 Neighboring gene protein phosphatase 4, regulatory subunit 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Identification of glycosyltransferase 8 family members as xylosyltransferases acting on O-glucosylated notch epidermal growth factor repeats. Sethi MK, et al. J Biol Chem, 2010 Jan 15. PMID 19940119, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables UDP-xylosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-xylosyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in O-glycan processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in O-glycan processing ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
glucoside xylosyltransferase 2; glycosyltransferase 8 domain containing 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    134903595..135006066
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039108771.2 → XP_038964699.1  glucoside xylosyltransferase 2 isoform X2

    Conserved Domains (1) summary
    cl11394
    Location:1 → 287
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

  2. XM_001066466.7 → XP_001066466.1  glucoside xylosyltransferase 2 isoform X1

    See identical proteins and their annotated locations for XP_001066466.1

    UniProtKB/TrEMBL
    A0A8I5ZMN1, D4A275
    Related
    ENSRNOP00000007419.3
    Conserved Domains (2) summary
    cd06430
    Location:111 → 414
    GT8_like_2; GT8_like_2 represents a subfamily of GT8 with unknown function
    COG1442
    Location:127 → 396
    RfaJ; Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis]

RNA

  1. XR_005503781.2 RNA Sequence

  2. XR_005503782.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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