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Myoz3 myozenin 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 689274, updated on 13-Apr-2024

Summary

Official Symbol
Myoz3provided by RGD
Official Full Name
myozenin 3provided by RGD
Primary source
RGD:1594778
See related
Ensembl:ENSRNOG00000019181 AllianceGenome:RGD:1594778
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable FATZ binding activity; actin binding activity; and telethonin binding activity. Predicted to be active in Z disc and actin cytoskeleton. Orthologous to human MYOZ3 (myozenin 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 361.7) See more
Orthologs
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Genomic context

See Myoz3 in Genome Data Viewer
Location:
18q12.1
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (56296565..56316582, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (54026133..54046151, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (55840535..55861217, complement)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene small integral membrane protein 3 Neighboring gene dynactin subunit 4 Neighboring gene RNA binding motif protein 22 Neighboring gene synaptopodin Neighboring gene uncharacterized LOC120098275

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables FATZ binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables actin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables telethonin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in modification of dendritic spine IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in Z disc IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Z disc ISO
Inferred from Sequence Orthology
more info
 
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001400829.1NP_001387758.1  myozenin-3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000018
    UniProtKB/TrEMBL
    A0A0H2UHR2
    Related
    ENSRNOP00000025989.3, ENSRNOT00000025989.5

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    56296565..56316582 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)