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H2ac21 H2A clustered histone 21 [ Rattus norvegicus (Norway rat) ]

Gene ID: 690102, updated on 13-Apr-2024

Summary

Official Symbol
H2ac21provided by RGD
Official Full Name
H2A clustered histone 21provided by RGD
Primary source
RGD:1584064
See related
AllianceGenome:RGD:1584064
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Hist2h2ab
Summary
Predicted to enable DNA binding activity. Predicted to be involved in heterochromatin assembly. Predicted to be located in nucleus. Predicted to be part of nucleosome. Orthologous to human H2AC21 (H2A clustered histone 21). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See H2ac21 in Genome Data Viewer
Location:
2q34
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (186468224..186468657)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (183779355..183779788)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (198359754..198360146)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene synaptic vesicle glycoprotein 2a Neighboring gene bolA family member 1 Neighboring gene histone H3-like Neighboring gene histone cluster 2 H2B family member E Neighboring gene H2A clustered histone 20

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables nucleosomal DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in heterochromatin formation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of nucleosome IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
H2A clustered histone 21
Names
histone cluster 2 H2A family member b
histone cluster 2, H2ab

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001111341.2NP_001104811.1  H2A clustered histone 21

    See identical proteins and their annotated locations for NP_001104811.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/Swiss-Prot
    Q64598
    UniProtKB/TrEMBL
    A6K356
    Conserved Domains (1) summary
    PTZ00017
    Location:1130
    PTZ00017; histone H2A; Provisional

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    186468224..186468657
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)