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Slc16a5 solute carrier family 16 member 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 690212, updated on 11-Apr-2024

Summary

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Official Symbol
Slc16a5provided by RGD
Official Full Name
solute carrier family 16 member 5provided by RGD
Primary source
RGD:1582896
See related
Ensembl:ENSRNOG00000023476 AllianceGenome:RGD:1582896
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be integral component of plasma membrane. Orthologous to human SLC16A5 (solute carrier family 16 member 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 46.0), Thymus (RPKM 13.2) and 1 other tissue See more
Orthologs
human mouse all
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Genomic context

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See Slc16a5 in Genome Data Viewer
Location:
10q32.1
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (101206371..101220300)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (100707434..100721338)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (104019888..104035735)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene potassium channel tetramerization domain containing 2 Neighboring gene tripartite motif protein 80 Neighboring gene armadillo repeat containing 7 Neighboring gene 5', 3'-nucleotidase, cytosolic Neighboring gene Jupiter microtubule associated homolog 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables monocarboxylic acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in monocarboxylic acid transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
monocarboxylate transporter 6
Names
solute carrier family 16 (monocarboxylate transporter), member 5
solute carrier family 16 (monocarboxylic acid transporters), member 5
solute carrier family 16, member 5 (monocarboxylic acid transporter 6)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109568.1 → NP_001103038.1  monocarboxylate transporter 6

    See identical proteins and their annotated locations for NP_001103038.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473948
    UniProtKB/TrEMBL
    A6HKN1, D4A3B5
    Related
    ENSRNOP00000035453.2, ENSRNOT00000032016.3
    Conserved Domains (2) summary
    cd06174
    Location:32 → 412
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00892
    Location:1 → 432
    2A0113; monocarboxylate transporter 1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    101206371..101220300
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063269884.1 → XP_063125954.1  monocarboxylate transporter 6 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

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