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Sertm1 serine-rich and transmembrane domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 690333, updated on 5-Mar-2024

Summary

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Official Symbol
Sertm1provided by RGD
Official Full Name
serine-rich and transmembrane domain containing 1provided by RGD
Primary source
RGD:1597355
See related
Ensembl:ENSRNOG00000014046 AllianceGenome:RGD:1597355
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to human SERTM1 (serine rich and transmembrane domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 64.8) See more
Orthologs
human mouse all
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Genomic context

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See Sertm1 in Genome Data Viewer
Location:
2q26
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (141237054..141256669, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (139086905..139106528, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (144303700..144323509, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene regulatory factor X-associated protein Neighboring gene uncharacterized LOC134485734 Neighboring gene uncharacterized LOC134485915 Neighboring gene uncharacterized LOC134485735

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
serine-rich and transmembrane domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109580.1 → NP_001103050.1  serine-rich and transmembrane domain-containing protein 1

    See identical proteins and their annotated locations for NP_001103050.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474003
    UniProtKB/TrEMBL
    A6JVE1, D3ZR22
    Related
    ENSRNOP00000018781.2, ENSRNOT00000018780.4
    Conserved Domains (1) summary
    pfam15872
    Location:1 → 106
    SRTM1; Serine-rich and transmembrane domain-containing protein 1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    141237054..141256669 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006232369.4 → XP_006232431.1  serine-rich and transmembrane domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006232431.1

    UniProtKB/TrEMBL
    A6JVE1, D3ZR22
    Conserved Domains (1) summary
    pfam15872
    Location:1 → 106
    SRTM1; Serine-rich and transmembrane domain-containing protein 1

  2. XM_006232370.4 → XP_006232432.1  serine-rich and transmembrane domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006232432.1

    UniProtKB/TrEMBL
    A6JVE1, D3ZR22
    Related
    ENSRNOP00000089551.1
    Conserved Domains (1) summary
    pfam15872
    Location:1 → 106
    SRTM1; Serine-rich and transmembrane domain-containing protein 1

  3. XM_017591119.3 → XP_017446608.1  serine-rich and transmembrane domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A6JVE1, D3ZR22
    Related
    ENSRNOP00000078208.1
    Conserved Domains (1) summary
    pfam15872
    Location:1 → 106
    SRTM1; Serine-rich and transmembrane domain-containing protein 1
Nucleotide Protein Strain
Heading Accession and Version

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