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Mansc1 MANSC domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 690606, updated on 13-Apr-2024

Summary

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Symbol
Mansc1provided by RGD
Full Name
MANSC domain containing 1provided by RGD
Primary source
RGD:1593458
See related
Ensembl:ENSRNOG00000028526 AllianceGenome:RGD:1593458
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be integral component of membrane. Orthologous to human MANSC1 (MANSC domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 15.9), Lung (RPKM 14.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Mansc1 in Genome Data Viewer
Location:
4q43
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (169170164..169190379, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (167438817..167459047, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (168363192..168382605, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene LDL receptor related protein 6 Neighboring gene uncharacterized LOC102551409 Neighboring gene BLOC-1 related complex subunit 5 Neighboring gene dual specificity phosphatase 16 Neighboring gene cAMP responsive element binding protein-like 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
MANSC domain-containing protein 1
NP_001103073.1
XP_006237600.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109603.3 → NP_001103073.1  MANSC domain-containing protein 1 precursor

    See identical proteins and their annotated locations for NP_001103073.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000004
    UniProtKB/TrEMBL
    A6IMD3, D4AE21
    Related
    ENSRNOP00000029997.2, ENSRNOT00000029510.5
    Conserved Domains (2) summary
    smart00765
    Location:23 → 116
    MANEC; The MANEC domain, formerly called MANSC
    cl07893
    Location:164 → 236
    AmyAc_family; Alpha amylase catalytic domain family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    169170164..169190379 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006237538.5 → XP_006237600.1  MANSC domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006237600.1

    UniProtKB/TrEMBL
    A6IMD3, D4AE21
    Conserved Domains (2) summary
    smart00765
    Location:23 → 116
    MANEC; The MANEC domain, formerly called MANSC
    cl07893
    Location:164 → 236
    AmyAc_family; Alpha amylase catalytic domain family
Nucleotide Protein Strain
Heading Accession and Version

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