Cog2 component of oligomeric golgi complex 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cog2provided by RGD
Official Full Name: component of oligomeric golgi complex 2provided by RGD
Primary source: RGD:1589822
See related: Ensembl:ENSRNOG00000018228 AllianceGenome:RGD:1589822
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in Golgi organization and intra-Golgi vesicle-mediated transport. Located in cytosol. Part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIq. Orthologous to human COG2 (component of oligomeric golgi complex 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 96.7), Thymus (RPKM 89.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 19q12

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	19	NC_086037.1 (69391305..69430072)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	19	NC_051354.1 (52493901..52532667)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	19	NC_005118.4 (57286955..57322853)

Chromosome 19 - NC_086037.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables protein-containing complex binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in Golgi organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in Golgi organization	ISO Inferred from Sequence Orthology more info
involved_in biological_process	ND No biological Data available more info
involved_in glycosylation	ISO Inferred from Sequence Orthology more info
involved_in intra-Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intra-Golgi vesicle-mediated transport	ISO Inferred from Sequence Orthology more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in retrograde transport, vesicle recycling within Golgi	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in Golgi stack	ISO Inferred from Sequence Orthology more info
part_of Golgi transport complex	IBA Inferred from Biological aspect of Ancestor more info
part_of Golgi transport complex	IDA Inferred from Direct Assay more info	PubMed
part_of Golgi transport complex	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: conserved oligomeric Golgi complex subunit 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001110494.1 → NP_001103964.1 conserved oligomeric Golgi complex subunit 2

See identical proteins and their annotated locations for NP_001103964.1

Status: PROVISIONAL

Source sequence(s)

CH474054

UniProtKB/TrEMBL

A6KJ08, D3ZT01

Related

ENSRNOP00000054881.2, ENSRNOT00000058074.3

Conserved Domains (2) summary

pfam06148
Location:15 → 147

COG2; COG (conserved oligomeric Golgi) complex component, COG2

pfam12022
Location:566 → 691

DUF3510; Domain of unknown function (DUF3510)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086037.1 Reference GRCr8

Range

69391305..69430072

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006255816.5 → XP_006255878.1 conserved oligomeric Golgi complex subunit 2 isoform X1

Conserved Domains (2) summary

pfam06148
Location:15 → 147

COG2; COG (conserved oligomeric Golgi) complex component, COG2

pfam12022
Location:566 → 691

DUF3510; Domain of unknown function (DUF3510)
XM_063278299.1 → XP_063134369.1 conserved oligomeric Golgi complex subunit 2 isoform X2