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Tm4sf20 transmembrane 4 L six family member 20 [ Rattus norvegicus (Norway rat) ]

Gene ID: 691066, updated on 11-Apr-2024

Summary

Symbol
Tm4sf20provided by RGD
Full Name
transmembrane 4 L six family member 20provided by RGD
Primary source
RGD:1588633
See related
Ensembl:ENSRNOG00000015460 AllianceGenome:RGD:1588633
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in negative regulation of proteolysis. Predicted to be located in endoplasmic reticulum membrane; focal adhesion; and plasma membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in specific language impairment. Orthologous to human TM4SF20 (transmembrane 4 L six family member 20). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 10.5), Lung (RPKM 6.6) and 9 other tissues See more
Orthologs
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Genomic context

See Tm4sf20 in Genome Data Viewer
Location:
9q34
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (91486847..91500745, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (84038715..84052615, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (88521193..88534710, complement)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene collagen type IV alpha 3 chain Neighboring gene mitochondrial fission factor Neighboring gene uncharacterized LOC120094722 Neighboring gene small cysteine and glycine repeat-containing protein 6-like Neighboring gene uncharacterized LOC120094723

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in negative regulation of proteolysis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 
located_in focal adhesion ISO
Inferred from Sequence Orthology
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
transmembrane 4 L6 family member 20
Names
transmembrane 4 L6 family member 20-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109618.1NP_001103088.1  transmembrane 4 L6 family member 20

    See identical proteins and their annotated locations for NP_001103088.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474004
    UniProtKB/TrEMBL
    A6JWB2, D3ZJ15
    Related
    ENSRNOP00000020880.4, ENSRNOT00000020880.6
    Conserved Domains (1) summary
    pfam05805
    Location:2220
    L6_membrane; L6 membrane protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    91486847..91500745 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)