Protein interactions
Protein |
Gene |
Interaction |
Pubs |
Nef
|
nef
|
A cell-based bimolecular fluorescence complementation assay demonstrates that HIV-1 Nef interacts with the Tec family members Bmx, Btk, and Itk but not Tec or Txk. Mutation A96I in the Tec SH3 domain dramatically enhances interaction with Nef |
PubMed
|
Pr55(Gag)
|
gag
|
Tec kinase chemical inhibitors diminish the recruitment of ITK to the plasma membrane perturbing HIV-1 Gag-ITK co-localization, disrupting F-actin polymerization, and inhibiting HIV-1 release and replication |
PubMed
|
Go to the HIV-1, Human Interaction Database