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Pgm2l1 phosphoglucomutase 2-like 1 [ Mus musculus (house mouse) ]

Gene ID: 70974, updated on 5-Mar-2024

Summary

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Official Symbol
Pgm2l1provided by MGI
Official Full Name
phosphoglucomutase 2-like 1provided by MGI
Primary source
MGI:MGI:1918224
See related
Ensembl:ENSMUSG00000030729 AllianceGenome:MGI:1918224
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
BM32A; 4931406N15Rik
Summary
Predicted to enable glucose-1,6-bisphosphate synthase activity. Predicted to be involved in organic substance metabolic process. Predicted to act upstream of or within glucose metabolic process. Is expressed in several structures, including nervous system; sensory organ; and urinary system. Orthologous to human PGM2L1 (phosphoglucomutase 2 like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cortex adult (RPKM 17.9), CNS E18 (RPKM 14.6) and 12 other tissues See more
Orthologs
human all
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Genomic context

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See Pgm2l1 in Genome Data Viewer
Location:
7 E2; 7 54.33 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (99876471..99928079)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (100227273..100278872)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene cyclin B1 pseudogene Neighboring gene predicted gene, 34877 Neighboring gene STARR-seq mESC enhancer starr_19666 Neighboring gene glutathione peroxidase 2, pseudogene 1 Neighboring gene STARR-positive B cell enhancer ABC_E4953 Neighboring gene procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III Neighboring gene protein phosphatase methylesterase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Rutledge EA, et al. Development, 2017 Sep 1. PMID 28705898, Free PMC Article
  2. ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease. Cozzolino F, et al. Hum Mol Genet, 2021 Jun 17. PMID 33601422
  3. The sperm-associated antigen 6 interactome and its role in spermatogenesis. Liu Y, et al. Reproduction, 2019 Aug. PMID 31146259, Free PMC Article
  4. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
  5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables glucose-1,6-bisphosphate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glucose-1,6-bisphosphate synthase activity ISO
Inferred from Sequence Orthology
more info
  
enables intramolecular phosphotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within glucose metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in organic substance metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glucose 1,6-bisphosphate synthase
NP_081905.1
XP_006508267.1
XP_006508268.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027629.3 → NP_081905.1  glucose 1,6-bisphosphate synthase

    See identical proteins and their annotated locations for NP_081905.1

    Status: VALIDATED

    Source sequence(s)
    AC121815, AC122269, AK016437, BB633030, CF531609, CK379061
    Consensus CDS
    CCDS40035.1
    UniProtKB/Swiss-Prot
    Q8CAA7
    Related
    ENSMUSP00000081998.4, ENSMUST00000084935.11
    Conserved Domains (1) summary
    PTZ00150
    Location:24 → 620
    PTZ00150; phosphoglucomutase-2-like protein; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    99876471..99928079
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006508205.3 → XP_006508268.1  glucose 1,6-bisphosphate synthase isoform X1

    See identical proteins and their annotated locations for XP_006508268.1

    UniProtKB/Swiss-Prot
    Q8CAA7
    Conserved Domains (1) summary
    PTZ00150
    Location:24 → 620
    PTZ00150; phosphoglucomutase-2-like protein; Provisional

  2. XM_006508204.3 → XP_006508267.1  glucose 1,6-bisphosphate synthase isoform X1

    See identical proteins and their annotated locations for XP_006508267.1

    UniProtKB/Swiss-Prot
    Q8CAA7
    Conserved Domains (1) summary
    PTZ00150
    Location:24 → 620
    PTZ00150; phosphoglucomutase-2-like protein; Provisional
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CAA7.1 GenPept UniProtKB/Swiss-Prot:Q8CAA7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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