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SHMT2 serine hydroxymethyltransferase [ Phaeodactylum tricornutum CCAP 1055/1 ]

Gene ID: 7196206, updated on 21-Dec-2023

Summary

Gene symbol
SHMT2
Gene description
serine hydroxymethyltransferase
Locus tag
PHATRDRAFT_54015
Gene type
protein coding
RNA name
serine hydroxymethyltransferase
RefSeq status
PROVISIONAL
Organism
Phaeodactylum tricornutum CCAP 1055/1 (strain: CCAP 1055/1)
Lineage
Eukaryota; Stramenopiles; Bacillariophyta; Bacillariophyceae; Bacillariophycidae; Naviculales; Phaeodactylaceae; Phaeodactylum
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Genomic context

Location:
chromosome: 1
Exon count:
2
Sequence:
Chromosome: 1; NC_011669.1 (1659736..1661562, complement)

Chromosome 1 - NC_011669.1Genomic Context describing neighboring genes Neighboring gene predicted protein Neighboring gene predicted protein Neighboring gene predicted protein Neighboring gene predicted protein

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cobalt ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables glycine hydroxymethyltransferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables serine binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in L-serine catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in folic acid metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in glycine biosynthetic process from serine IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Names
serine hydroxymethyltransferase
XP_002177340.1
  • serine hydroxymethyltransferase (aka glycine hydroxymethyltransferase) catalyzes the conversion of glycine to serine. In this model, the presence of a mitochondrial transit peptide suggests this isozyme functions in photorespiration, catalyzing the conversion of two glycine to one serine with the enzyme glycine decarboxylase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_011669.1 Reference assembly

    Range
    1659736..1661562 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002177304.1XP_002177340.1  serine hydroxymethyltransferase [Phaeodactylum tricornutum CCAP 1055/1]

    See identical proteins and their annotated locations for XP_002177340.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    B7FQ66
    Conserved Domains (2) summary
    PLN03226
    Location:16493
    PLN03226; serine hydroxymethyltransferase; Provisional
    cl18945
    Location:30428
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...