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Armt1 acidic residue methyltransferase 1 [ Mus musculus (house mouse) ]

Gene ID: 73419, updated on 25-May-2024

Summary

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Official Symbol
Armt1provided by MGI
Official Full Name
acidic residue methyltransferase 1provided by MGI
Primary source
MGI:MGI:1920669
See related
Ensembl:ENSMUSG00000061759 AllianceGenome:MGI:1920669
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700052N19Rik
Summary
Predicted to enable enzyme binding activity; methyltransferase activity; and phosphatase activity. Predicted to be involved in methylation and regulation of response to DNA damage stimulus. Predicted to act upstream of or within cellular response to DNA damage stimulus. Orthologous to human ARMT1 (acidic residue methyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 19.5), liver E14 (RPKM 6.3) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Armt1 in Genome Data Viewer
Location:
10 A1; 10 2.06 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (4382572..4405140)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (4429275..4455140)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_25640 Neighboring gene A kinase anchor protein 12 Neighboring gene predicted gene, 40592 Neighboring gene STARR-seq mESC enhancer starr_25637 Neighboring gene STARR-positive B cell enhancer ABC_E11428 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:5999414-5999597 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:5988889-5989072 Neighboring gene STARR-seq mESC enhancer starr_25630 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:5958087-5958270 Neighboring gene zinc finger and BTB domain containing 2 Neighboring gene STARR-positive B cell enhancer ABC_E2315 Neighboring gene required for meiotic nuclear division 1 homolog Neighboring gene STARR-seq mESC enhancer starr_25628 Neighboring gene coiled-coil domain containing 170 Neighboring gene predicted gene, 22739 Neighboring gene STARR-seq mESC enhancer starr_25624 Neighboring gene glutathione S-transferase, pi 1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  4. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  5. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1) 

General gene information

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Markers

Homology

Clone Names

  • MGC102037

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables S-adenosylmethionine-dependent methyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein carboxyl O-methyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA damage response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in DNA damage response ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
damage-control phosphatase ARMT1
Names
UPF0364 protein C6orf211 homolog
protein-glutamate O-methyltransferase
sugar phosphate phosphatase ARMT1
NP_077223.2
XP_011241402.1
XP_011241403.1
XP_030101175.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024261.2 → NP_077223.2  damage-control phosphatase ARMT1

    See identical proteins and their annotated locations for NP_077223.2

    Status: VALIDATED

    Source sequence(s)
    BC099894, BU148062
    Consensus CDS
    CCDS56676.1
    UniProtKB/Swiss-Prot
    A6H630, Q499H1, Q99M05, Q9D9L4
    Related
    ENSMUSP00000093581.5, ENSMUST00000095893.11
    Conserved Domains (1) summary
    pfam01937
    Location:20 → 417
    DUF89; Protein of unknown function DUF89

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    4382572..4405140
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011243100.4 → XP_011241402.1  damage-control phosphatase ARMT1 isoform X1

    See identical proteins and their annotated locations for XP_011241402.1

    Conserved Domains (1) summary
    pfam01937
    Location:50 → 331
    DUF89; Protein of unknown function DUF89

  2. XM_030245315.2 → XP_030101175.1  damage-control phosphatase ARMT1 isoform X2

    Conserved Domains (1) summary
    pfam01937
    Location:1 → 298
    DUF89; Protein of unknown function DUF89

  3. XM_011243101.4 → XP_011241403.1  damage-control phosphatase ARMT1 isoform X1

    See identical proteins and their annotated locations for XP_011241403.1

    Conserved Domains (1) summary
    pfam01937
    Location:50 → 331
    DUF89; Protein of unknown function DUF89
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A6H630.1 GenPept UniProtKB/Swiss-Prot:A6H630

Gene LinkOut

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