MMP16 matrix metallopeptidase 16 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: MMP16provided by VGNC
Official Full Name: matrix metallopeptidase 16provided by VGNC
Primary source: VGNC:VGNC:6570
Locus tag: CK820_G0001771
See related: Ensembl:ENSPTRG00000020403
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	7	NC_072405.2 (98307788..98595055, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	8	NC_072406.1 (102891279..103178672, complement)

Chromosome 7 - NC_072405.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

AB021228 (e-PCR)
- UniSTS:163337

D5Wox36 (e-PCR)
- UniSTS:239940

Mmp16 (e-PCR), detects polymorphism
- UniSTS:495993

RH120085 (e-PCR)
- UniSTS:133515

D8S1404E (e-PCR)
- UniSTS:151198

WI-21150 (e-PCR)
- UniSTS:15287

A008X11 (e-PCR)
- UniSTS:59849

RH120010 (e-PCR)
- UniSTS:133334

RH123289 (e-PCR)
- UniSTS:135666

MMP16_920 (e-PCR)
- UniSTS:277491

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables metalloendopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in collagen catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in extracellular matrix organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in skeletal system development	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular matrix	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: matrix metalloproteinase-16

Names: matrix metallopeptidase 16 (membrane-inserted); matrix metalloproteinase 16

XP_001136497.3

EC 3.4.24.-

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072405.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

98307788..98595055 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001136497.8 → XP_001136497.3 matrix metalloproteinase-16

UniProtKB/TrEMBL

A0A2J8PLE2, A0A803KLQ7, K7ASR0, K7BXK7

Conserved Domains (5) summary

PHA03247
Location:292 → 338

PHA03247; large tegument protein UL36; Provisional

cd00094
Location:340 → 532

HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...

pfam00413
Location:126 → 291

Peptidase_M10; Matrixin

pfam01471
Location:42 → 96

PG_binding_1; Putative peptidoglycan binding domain

pfam11857
Location:538 → 607

DUF3377; Domain of unknown function (DUF3377)