U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Arxes1 adipocyte-related X-chromosome expressed sequence 1 [ Mus musculus (house mouse) ]

Gene ID: 76219, updated on 8-Feb-2024

Summary

Go to the top of the page Help
Official Symbol
Arxes1provided by MGI
Official Full Name
adipocyte-related X-chromosome expressed sequence 1provided by MGI
Primary source
MGI:MGI:1923469
See related
Ensembl:ENSMUSG00000048355 AllianceGenome:MGI:1923469
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Spcs3; Spc22/23; 6530401D17Rik
Summary
Acts upstream of or within fat cell differentiation. Located in endoplasmic reticulum. Is expressed in axial musculature; central nervous system; cornea stroma; and dorsal root ganglion. [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Arxes1 in Genome Data Viewer
Location:
X F1; X 57.36 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (134934116..134935695)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (136033367..136034946)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 31214 Neighboring gene adipocyte-related X-chromosome expressed sequence 2 Neighboring gene predicted gene, 54084 Neighboring gene brain expressed X-linked 2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Arxes: retrotransposed genes required for adipogenesis. Prokesch A, et al. Nucleic Acids Res, 2011 Apr. PMID 21177646, Free PMC Article
  2. A 1.1-Mb segmental deletion on the X chromosome causes meiotic failure in male mice. Zhou J, et al. Biol Reprod, 2013 Jun. PMID 23677977, Free PMC Article
  3. Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells. Zhang M, et al. Mol Cell Proteomics, 2014 Nov. PMID 25044020, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within fat cell differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein targeting to ER IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in signal peptide processing IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
part_of signal peptidase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
adipocyte-related X-chromosome expressed sequence 1
Names
SPase 22 kDa subunit
SPase 22/23 kDa subunit
microsomal signal peptidase 22/23 kDa subunit
microsomal signal peptidase 23 kDa subunit

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029541.3 → NP_083817.1  adipocyte-related X-chromosome expressed sequence 1

    See identical proteins and their annotated locations for NP_083817.1

    Status: VALIDATED

    Source sequence(s)
    AK018307, AL671914, BY287880, CF751524
    Consensus CDS
    CCDS53192.1
    UniProtKB/Swiss-Prot
    B1AUR7, C0HK79, C0HK80, Q8BK31, Q9D365, Q9D6F2
    Related
    ENSMUSP00000062660.3, ENSMUST00000057625.3
    Conserved Domains (1) summary
    pfam04573
    Location:4 → 173
    SPC22; Signal peptidase subunit

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    134934116..134935695
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_003641.1: Suppressed sequence

    Description
    NR_003641.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
C0HK79.1 GenPept UniProtKB/Swiss-Prot:C0HK79

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous