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galc galactosylceramidase [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 779723, updated on 25-Apr-2024

Summary

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Official Symbol
galcprovided by Xenbase
Official Full Name
galactosylceramidaseprovided by Xenbase
Primary source
Xenbase:XB-GENE-1000107
See related
Ensembl:ENSXETG00000016608
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
GALCERase
Orthologs
human mouse all
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Genomic context

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See galc in Genome Data Viewer
Location:
chromosome: 8
Exon count:
18
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (85726354..85751556, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 8 NC_030684.1 (64644414..64669653, complement)

Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene serine/threonine-protein kinase N1-like Neighboring gene uncharacterized protein K02A2.6-like Neighboring gene G protein-coupled receptor 65 Neighboring gene potassium channel, two pore domain subfamily K, member 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC145326

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables galactosylceramidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables galactosylceramidase activity IEA
Inferred from Electronic Annotation
more info
  
enables galactosylceramidase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in galactosylceramide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within galactosylceramide catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within galactosylceramide catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within lipid catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sphingolipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in lysosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in lysosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
galactocerebrosidase
NP_001072270.1
XP_012824052.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001078802.1 → NP_001072270.1  galactocerebrosidase precursor

    See identical proteins and their annotated locations for NP_001072270.1

    Status: PROVISIONAL

    Source sequence(s)
    BC121269
    UniProtKB/Swiss-Prot
    Q0VA39
    UniProtKB/TrEMBL
    F6WLC6
    Related
    ENSXETP00000036227.4, ENSXETT00000036227.5
    Conserved Domains (2) summary
    pfam02057
    Location:59 → 341
    Glyco_hydro_59; Glycosyl hydrolase family 59
    pfam17387
    Location:349 → 464
    Glyco_hydro_59M; Glycosyl hydrolase family 59 central domain

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    85726354..85751556 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012968598.3 → XP_012824052.2  galactocerebrosidase isoform X1

    UniProtKB/TrEMBL
    A0A6I8QBD8, F6WLC6
    Related
    ENSXETP00000066849.2, ENSXETT00000100318.2
    Conserved Domains (2) summary
    pfam02057
    Location:59 → 340
    Glyco_hydro_59; Glycosyl hydrolase family 59
    pfam17387
    Location:348 → 463
    Glyco_hydro_59M; Glycosyl hydrolase family 59 central domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0VA39.1 GenPept UniProtKB/Swiss-Prot:Q0VA39

Gene LinkOut

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