Stpg1 sperm tail PG rich repeat containing 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Stpg1provided by MGI
Official Full Name: sperm tail PG rich repeat containing 1provided by MGI
Primary source: MGI:MGI:1926056
See related: Ensembl:ENSMUSG00000028801 AllianceGenome:MGI:1926056
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Mapo2; 4930403G18Rik; 4930555I21Rik
Summary: Predicted to be involved in positive regulation of apoptotic process and positive regulation of mitochondrial membrane permeability involved in apoptotic process. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytoplasm and nucleus. Orthologous to human STPG1 (sperm tail PG-rich repeat containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward testis adult (RPKM 36.0) See more
Orthologs: human all
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Genomic context

Location:: 4 D3; 4 67.7 cM

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	4	NC_000070.7 (135221971..135265015)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	4	NC_000070.6 (135494670..135537803)

Chromosome 4 - NC_000070.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

MAPO2 gene product might positively contribute to the induction of apoptosis triggered by O-methylguanine
Title: The identification of a novel gene, MAPO2, that is involved in the induction of apoptosis triggered by O⁶-methylguanine.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within apoptotic process	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of mitochondrial membrane permeability involved in apoptotic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of mitochondrial membrane permeability involved in apoptotic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: O(6)-methylguanine-induced apoptosis 2

Names: O6-methylguanine-induced apoptosis 2; UPF0490 protein C1orf201 homolog; sperm-tail PG-rich repeat-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001419281.1 → NP_001406210.1 O(6)-methylguanine-induced apoptosis 2 isoform a

Status: VALIDATED

Source sequence(s)

AL670720

UniProtKB/Swiss-Prot

Q9D2F5
NM_001419282.1 → NP_001406211.1 O(6)-methylguanine-induced apoptosis 2 isoform b

Status: VALIDATED

Source sequence(s)

AL670720
NM_001419286.1 → NP_001406215.1 O(6)-methylguanine-induced apoptosis 2 isoform c

Status: VALIDATED

Source sequence(s)

AL670720
NM_001419287.1 → NP_001406216.1 O(6)-methylguanine-induced apoptosis 2 isoform c

Status: VALIDATED

Source sequence(s)

AL670720
NM_030189.4 → NP_084465.1 O(6)-methylguanine-induced apoptosis 2 isoform a

See identical proteins and their annotated locations for NP_084465.1

Status: VALIDATED

Source sequence(s)

AL670720

Consensus CDS

CCDS18787.1

UniProtKB/Swiss-Prot

Q9D2F5

UniProtKB/TrEMBL

A6H5V9

Related

ENSMUSP00000067647.3, ENSMUST00000063707.3