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PF3D7_1020800 dihydrolipoamide acyltransferase component E2 [ Plasmodium falciparum 3D7 ]

Gene ID: 810359, updated on 16-Oct-2023

Summary

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Gene symbol
PF3D7_1020800
Gene description
dihydrolipoamide acyltransferase component E2
Locus tag
PF3D7_1020800
Gene type
protein coding
RNA name
dihydrolipoamide acyltransferase component E2
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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Location:
chromosome: 10
Exon count:
11
Sequence:
Chromosome: 10; NC_037281.1 (840212..843403)

Chromosome 10 - NC_037281.1Genomic Context describing neighboring genes Neighboring gene conserved Plasmodium membrane protein, unknown function Neighboring gene hypothetical protein Neighboring gene ADP-ribosylation factor Neighboring gene conserved protein, unknown function

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037281.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The malaria parasite Plasmodium falciparum has only one pyruvate dehydrogenase complex, which is located in the apicoplast. Foth BJ, et al. Mol Microbiol, 2005 Jan. PMID 15612915
  2. Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites. Boucher MJ, et al. PLoS Biol, 2018 Sep. PMID 30212465, Free PMC Article
  3. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables dihydrolipoyllysine-residue acetyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in apicoplast HDA PubMed 
located_in apicoplast IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
dihydrolipoamide acyltransferase component E2
XP_001347486.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_037281.1 Reference assembly

    Range
    840212..843403
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001347450.2 → XP_001347486.2  dihydrolipoamide acyltransferase component E2 [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001347486.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A024WRD0, A0A0L1IB96, A0A2I0BR44, Q5VGY2, Q8IJJ4, W7FCH8, W7FUN9, W7JXQ5
    Conserved Domains (2) summary
    cd06849
    Location:53 → 126
    lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...
    PRK11856
    Location:202 → 633
    PRK11856; branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed
Nucleotide Protein
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