U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PF3D7_1113700 glyoxalase I [ Plasmodium falciparum 3D7 ]

Gene ID: 810692, updated on 17-May-2024

Summary

Go to the top of the page Help
Gene symbol
PF3D7_1113700
Gene description
glyoxalase I
Primary source
PlasmoDB:PF3D7_1113700
Locus tag
PF3D7_1113700
Gene type
protein coding
RNA name
glyoxalase I
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 11
Exon count:
1
Sequence:
Chromosome: 11; NC_037282.1 (529493..530563)

Chromosome 11 - NC_037282.1Genomic Context describing neighboring genes Neighboring gene GTP-binding protein, putative Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene conserved Plasmodium membrane protein, unknown function Neighboring gene mitogen-activated protein kinase 2

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_037282.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The cytosolic glyoxalases of Plasmodium falciparum are dispensable during asexual blood-stage development. Wezena CA, et al. Microb Cell, 2017 Nov 20. PMID 29354648, Free PMC Article
  2. Tight-binding inhibitors efficiently inactivate both reaction centers of monomeric Plasmodium falciparum glyoxalase 1. Urscher M, et al. FEBS J, 2012 Jul. PMID 22607473
  3. Glyoxalase I of the malarial parasite Plasmodium falciparum: evidence for subunit fusion. Iozef R, et al. FEBS Lett, 2003 Nov 20. PMID 14623080
  4. Characterization of the glyoxalases of the malarial parasite Plasmodium falciparum and comparison with their human counterparts. Akoachere M, et al. Biol Chem, 2005 Jan. PMID 15843146
  5. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables lactoylglutathione lyase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within glutathione metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
glyoxalase I
XP_001347816.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_037282.1 Reference assembly

    Range
    529493..530563
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001347780.1 → XP_001347816.1  glyoxalase I [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001347816.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A024UY82, A0A024VQJ5, A0A024W659, A0A024WQ63, A0A024X872, A0A0L1IDT6, A0A0L7KAB4, Q71KM3, Q8IIM5, W4IDW9, W4IS11, W7FCN1, W7FNZ0, W7JB92, W7KEP1
    Conserved Domains (1) summary
    cd07233
    Location:180 → 347
    GlxI_Zn; Glyoxalase I that uses Zn(++) as cofactor
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous