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PF3D7_1212000 glutathione peroxidase-like thioredoxin peroxidase [ Plasmodium falciparum 3D7 ]

Gene ID: 811172, updated on 16-Oct-2023

Summary

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Gene symbol
PF3D7_1212000
Gene description
glutathione peroxidase-like thioredoxin peroxidase
Locus tag
PF3D7_1212000
Gene type
protein coding
RNA name
glutathione peroxidase-like thioredoxin peroxidase
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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Genomic context

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Location:
chromosome: 12
Exon count:
3
Sequence:
Chromosome: 12; NC_037284.1 (534912..535915, complement)

Chromosome 12 - NC_037284.1Genomic Context describing neighboring genes Neighboring gene polyubiquitin Neighboring gene non-SERCA-type Ca2+ -transporting P-ATPase Neighboring gene peripheral plastid protein 1, putative Neighboring gene conserved protein, unknown function

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037284.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A novel trafficking pathway in Plasmodium falciparum for the organellar localization of glutathione peroxidase-like thioredoxin peroxidase. Chaudhari R, et al. FEBS J, 2012 Oct. PMID 22889167
  2. The putative glutathione peroxidase gene of Plasmodium falciparum codes for a thioredoxin peroxidase. Sztajer H, et al. J Biol Chem, 2001 Mar 9. PMID 11087748
  3. Membrane and luminal proteins reach the apicoplast by different trafficking pathways in the malaria parasite Plasmodium falciparum. Chaudhari R, et al. PeerJ, 2017. PMID 28462015, Free PMC Article
  4. Compartmentation of redox metabolism in malaria parasites. Kehr S, et al. PLoS Pathog, 2010 Dec 23. PMID 21203490, Free PMC Article
  5. Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites. Boucher MJ, et al. PLoS Biol, 2018 Sep. PMID 30212465, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data indicate that glutathione peroxidase-like thioredoxin peroxidase (PfTPx(Gl)), is localized to the apicoplast, the mitochondrion and the cytosol
    Title: A novel trafficking pathway in Plasmodium falciparum for the organellar localization of glutathione peroxidase-like thioredoxin peroxidase.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables thioredoxin peroxidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in apicoplast HDA PubMed 
located_in apicoplast IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
glutathione peroxidase-like thioredoxin peroxidase
XP_001350528.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_037284.1 Reference assembly

    Range
    534912..535915 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001350492.1 → XP_001350528.1  glutathione peroxidase-like thioredoxin peroxidase [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001350528.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A024VNQ3, A0A024WNL5, A0A024X5R4, A0A0L7KCK2, A0A2I0BYP3, Q27742, Q8I5T2, W4IDL5, W7F4V6, W7G2U4, W7JKN3
    Conserved Domains (1) summary
    PTZ00056
    Location:26 → 205
    PTZ00056; glutathione peroxidase; Provisional
Nucleotide Protein
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